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墨西哥一株引起脑膜炎的结核分枝杆菌MYC004的基因组测序与注释

Sequencing and Annotation of the Genome of Mycobacterium tuberculosis MYC004, a Strain Causing Meningitis in Mexico.

作者信息

Guillén-Nepita Ana Laura, Negrete-Paz Andrea Monserrat, Vázquez-Marrufo Gerardo, Cruz-Hernández Andrés, Fresia Pablo, Naya Hugo, Vázquez-Garcidueñas Ma Soledad

机构信息

División de Estudios de Posgrado, Facultad de Ciencias Médicas y Biológicas Dr. Ignacio Chávez, Universidad Michoacana de San Nicolás de Hidalgo, Morelia, Michoacán, Mexico.

Facultad de Ingeniería, Universidad Autónoma de Querétaro, Centro Universitario, Santiago de Querétaro, Mexico.

出版信息

Genome Announc. 2018 Jun 21;6(25):e00523-18. doi: 10.1128/genomeA.00523-18.

DOI:10.1128/genomeA.00523-18
PMID:29930042
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6013621/
Abstract

strain MYC004 was isolated from a Mexican patient with tuberculous meningitis, the most aggressive form of tuberculosis. The draft genome sequence is the first of a meningeal strain of reported from Latin America and consists of 4,411,530 bp, including 4,251 protein-encoding genes.

摘要

菌株MYC004是从一名患有结核性脑膜炎（结核病最具侵袭性的形式）的墨西哥患者身上分离出来的。该基因组草图序列是拉丁美洲报道的第一例脑膜菌株的序列，由4,411,530个碱基对组成，包括4,251个蛋白质编码基因。