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髂动脉闭塞性疾病血管内治疗结局的相关因素:单中心经验

Factors associated with outcome of endovascular treatment of iliac occlusive disease: a single-center experience.

作者信息

Soares Rafael de Athayde, Matielo Marcelo Fernando, Brochado-Neto Francisco Cardoso, Cury Marcus Vinícius Martins, Costa Veridiana Borges, Sanjuan Maria Clara Pereira, Pecego Christiano Stchelkunoff, Sacilotto Roberto

机构信息

Serviço de Cirurgia Vascular e Endovascular, Hospital do Servidor Público Estadual de São Paulo, São Paulo, SP, Brasil.

出版信息

J Vasc Bras. 2018 Jan-Mar;17(1):3-9. doi: 10.1590/1677-5449.003817.

Abstract

BACKGROUND

Endovascular treatment (ET) of iliac occlusive disease (IOD) is well established in literature. Use of stents in IOD has achieved long-term limb salvage and patency rates similar to those of open surgery, with lower morbidity and mortality rates.

OBJECTIVES

To report the long-term outcomes, particularly limb salvage and patency rates, of ET for IOD and the factors associated with these outcomes.

METHODS

This retrospective cohort study included patients with IOD who underwent iliac angioplasty (IA), between January 2009 and January 2015. Patients with critical limb ischemia or incapacitating claudication were included.

RESULTS

In total, 48 IA procedures were performed in 46 patients, with an initial technical success rate of 95.83%. Failure occurred in two patients, who were excluded, leaving 44 patients and 46 IA. The primary patency, secondary patency, limb salvage, and survival rates at 1200 days were 88%, 95.3%, 86.3%, and 69.9%, respectively. Univariate and multivariate Cox regression revealed that the primary patency rate was significantly worse in patients with TASC type C/D than in patients with TASC type A/B (p = 0.044). Analysis of factors associated with major amputation using Cox regression showed that the rate of limb loss was greater in patients with TASC type C/D (p = 0.043). Male gender was associated with reduced survival (p = 0.011).

CONCLUSIONS

TASC type C/D was associated with a higher number of reinterventions and with worse limb loss and primary patency rates. Male gender was associated with a worse survival rate after ET of IOD.

摘要

背景

髂动脉闭塞性疾病(IOD)的血管内治疗(ET)在文献中已有充分记载。在IOD中使用支架已实现与开放手术相似的长期肢体挽救率和通畅率,且发病率和死亡率更低。

目的

报告IOD的ET的长期结局,尤其是肢体挽救率和通畅率,以及与这些结局相关的因素。

方法

这项回顾性队列研究纳入了2009年1月至2015年1月期间接受髂动脉血管成形术(IA)的IOD患者。纳入严重肢体缺血或致残性间歇性跛行患者。

结果

46例患者共进行了48次IA手术,初始技术成功率为95.83%。2例患者手术失败,被排除在外,剩余44例患者和46次IA手术。1200天时的原发性通畅率、继发性通畅率、肢体挽救率和生存率分别为88%、95.3%、86.3%和69.9%。单因素和多因素Cox回归显示,TASC C/D型患者的原发性通畅率显著低于TASC A/B型患者(p = 0.044)。使用Cox回归分析与大截肢相关的因素表明,TASC C/D型患者的肢体丢失率更高(p = 0.043)。男性与生存率降低相关(p = 0.011)。

结论

TASC C/D型与更高的再次干预次数、更差的肢体丢失率和原发性通畅率相关。男性与IOD的ET术后较差的生存率相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b214/5990269/f0f0f64ae0bf/jvb-17-01-003-g01.jpg

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