Kayatani Hitoshi, Nitta Naoki, Moritani Suzuko, Nozaki Kazuhiko
Department of Neurosurgery, Shiga University of Medical Science, Seta-Tsukinowa-Cho, Otsu, Shiga, Japan.
National Epilepsy Center, Shizuoka Institute of Epilepsy and Neurological Disorders, Aoi-ku, Shizuoka, Japan.
Surg Neurol Int. 2018 May 25;9:110. doi: 10.4103/sni.sni_289_17. eCollection 2018.
Primary lymphomas in the choroid plexus are much less frequent than primary lymphomas in the brain parenchyma.
A 66-year-old male patient was referred to our department with a right intraventricular mass that had been diagnosed by biopsy at another hospital as anaplastic ependymoma. The patient underwent subtotal removal of the tumor via a transcortical inferior temporal gyrus approach. The mass was attached to the choroid plexus in the right atrium. Histopathological examination showed diffuse large B-cell lymphoma. Ophthalmological examination, blood tests, computed tomography of the whole body, and bone marrow biopsy did not show any other lesion, leading to the diagnosis of primary choroid plexus lymphoma. The patient underwent chemotherapy with three courses of high-dose methotrexate and one course of carboplatin and etoposide followed by whole-brain irradiation (1.8 Gy × 22).
We present a rare case of primary choroid plexus lymphoma, which should be considered in the differential diagnosis of choroid plexus tumors.
脉络丛原发性淋巴瘤比脑实质原发性淋巴瘤少见得多。
一名66岁男性患者因右脑室内肿块被转诊至我科，该肿块在另一家医院经活检诊断为间变性室管膜瘤。患者通过经皮质颞下回入路接受了肿瘤次全切除术。肿块附着于右心房的脉络丛。组织病理学检查显示为弥漫性大B细胞淋巴瘤。眼科检查、血液检查、全身计算机断层扫描和骨髓活检均未发现任何其他病变，从而诊断为原发性脉络丛淋巴瘤。患者接受了三个疗程的大剂量甲氨蝶呤化疗和一个疗程的卡铂及依托泊苷化疗，随后进行全脑照射（1.8 Gy×22）。
我们报告了一例罕见的原发性脉络丛淋巴瘤病例，在脉络丛肿瘤的鉴别诊断中应考虑到该病。
