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[脑烟碱型乙酰胆碱受体及其在中枢心血管调节中的功能]

[Brain nicotinic acetylcholine receptors and their functions in special reference to central cardiovascular regulation].

作者信息

Kubo T

出版信息

Nihon Yakurigaku Zasshi. 1985 Jun;85(6):425-33. doi: 10.1254/fpj.85.425.

DOI:10.1254/fpj.85.425
PMID:2993138
Abstract

The nicotinic acetylcholine receptors present in the mammalian brain have received less attention than those in other areas of the nervous system. However, recent studies have reported the pharmacological character and regional distribution of a high-affinity binding of [3H]acetylcholine or [3H]nicotine. In this review, the pharmacological characters and physiological functions of the brain nicotinic receptors were discussed with special reference to central cardiovascular regulation.

摘要

哺乳动物大脑中存在的烟碱型乙酰胆碱受体受到的关注比神经系统其他区域的此类受体要少。然而,最近的研究报告了[3H]乙酰胆碱或[3H]尼古丁高亲和力结合的药理学特性和区域分布。在这篇综述中,特别参照中枢心血管调节,讨论了脑烟碱受体的药理学特性和生理功能。

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