Tanaka K, Mori W
Jpn J Cancer Res. 1985 Jul;76(7):603-7.
Hepatitis B surface antigen (HBs-Ag) was detected histologically (by victoria blue-nuclear fast red staining) in the liver in 20-40% of liver cirrhosis and/or hepatocellular carcinoma (hepatoma) cases. In hepatoma cases, HBs-Ag was usually found in non-cancerous areas of the liver. However, some HBs-Ag positive cells were also found dispersed in cancerous areas; these were regarded as HBs-Ag-infected non-cancerous hepatic cells remaining undestroyed. There were a few cases where inconsistency was found between the results of the immunofluorescence technique using anti HBs-Ag serum and victoria blue staining in detecting HBs-Ag. This phenomenon was rare in non-cancerous areas, but was relatively frequent in cancerous areas.
通过组织学方法（维多利亚蓝-核固红染色）在20%-40%的肝硬化和/或肝细胞癌（肝癌）病例的肝脏中检测到乙肝表面抗原（HBs-Ag）。在肝癌病例中，HBs-Ag通常在肝脏的非癌区域发现。然而，也发现一些HBs-Ag阳性细胞分散在癌区域；这些被认为是未被破坏的受HBs-Ag感染的非癌肝细胞。在使用抗HBs-Ag血清的免疫荧光技术和维多利亚蓝染色检测HBs-Ag的结果之间，有少数病例发现不一致。这种现象在非癌区域很少见，但在癌区域相对常见。
