Fed Regist. 2018 Feb 1;83(22):4580-5.
The Administrator of the Drug Enforcement Administration is issuing this temporary scheduling order to schedule seven fentanyl-related substances in schedule I. These seven substances are: N-(1-phenethylpiperidin-4-yl)-N-phenylpentanamide (valeryl fentanyl), N-(4-fluorophenyl)N-(1-phenethylpiperidin-4-yl)butyramide (para-fluorobutyryl fentanyl), N-(4-methoxyphenyl)-N-(1-phenethylpiperidin-4-yl)butyramide (para-methoxybutyryl fentanyl), N-(4-chlorophenyl)-N-(1-phenethylpiperidin-4-yl)isobutyramide (para-chloroisobutyryl fentanyl), N-(1-phenethylpiperidin-4-yl)-N-phenylisobutyramide (isobutyryl fentanyl), N-(1-phenethylpiperidin-4-yl)-N-phenylcyclopentanecarboxamide (cyclopentyl fentanyl), and N-(2- fluorophenyl)-2-methoxy-N-(1-phenethylpiperidin-4-yl)acetamide (ocfentanil). This action is based on a finding by the Administrator that the placement of these seven synthetic opioids in schedule I of the Controlled Substances Act is necessary to avoid an imminent hazard to the public safety. As a result of this order, the regulatory controls and administrative, civil, and criminal sanctions applicable to schedule I controlled substances will be imposed on persons who handle (manufacture, distribute, reverse distribute, import, export, engage in research, conduct instructional activities or chemical analysis, or possess), or propose to handle, valeryl fentanyl, para-fluorobutyryl fentanyl, para-methoxybutyryl fentanyl, para-chloroisobutyryl fentanyl, isobutyryl fentanyl, cyclopentyl fentanyl, and ocfentanil.
美国药品执法管理局局长发布本临时管制令,将七种与芬太尼相关的物质列为一类管制物质。这七种物质分别是:N-(1-苯乙基哌啶-4-基)-N-苯基戊酰胺(戊酰芬太尼)、N-(4-氟苯基)-N-(1-苯乙基哌啶-4-基)丁酰胺(对氟丁酰芬太尼)、N-(4-甲氧基苯基)-N-(1-苯乙基哌啶-4-基)丁酰胺(对甲氧基丁酰芬太尼)、N-(4-氯苯基)-N-(1-苯乙基哌啶-4-基)异丁酰胺(对氯异丁酰芬太尼)、N-(1-苯乙基哌啶-4-基)-N-苯基异丁酰胺(异丁酰芬太尼)、N-(1-苯乙基哌啶-4-基)-N-苯基环戊烷甲酰胺(环戊基芬太尼)以及N-(2-氟苯基)-2-甲氧基-N-(1-苯乙基哌啶-4-基)乙酰胺(奥芬太尼)。该行动基于局长的一项认定,即将这七种合成阿片类物质列为《管制物质法》一类管制物质对于避免对公众安全造成紧迫危害而言是必要的。根据本命令,适用于一类管制物质的监管控制措施以及行政、民事和刑事制裁将施加于处理(制造、分销、反向分销、进口、出口、从事研究、开展教学活动或化学分析、或持有)或打算处理戊酰芬太尼、对氟丁酰芬太尼、对甲氧基丁酰芬太尼、对氯异丁酰芬太尼、异丁酰芬太尼、环戊基芬太尼和奥芬太尼的人员。