γ-柔红霉素对映选择性合成的模型反应：邻醌醚的立体特异性分子内光氧化环化反应生成螺缩醛。
Model Reactions for the Enantioselective Synthesis of γ-Rubromycin: Stereospecific Intramolecular Photoredox Cyclization of an ortho-Quinone Ether to a Spiroacetal.
机构信息
Department of Chemistry , Tokyo Institute of Technology , 2-12-1 O-okayama , Meguro-ku , Tokyo 152-8551 , Japan.
出版信息
Org Lett. 2018 Jul 6;20(13):3928-3932. doi: 10.1021/acs.orglett.8b01475. Epub 2018 Jun 22.
PMID:29932661
Abstract
A model study for the enantioselective total synthesis of γ-rubromycin has revealed a promising approach for constructing the chiral, nonracemic bicyclic spiroacetal via the stereospecific photoredox reaction of 1,2-naphthoquinone ether.
摘要
通过对 1,2-萘醌醚的立体特异性光氧化还原反应的研究，为γ-柔红霉素的对映选择性全合成建立了一个模型，该模型为构建手性非外消旋双环螺缩酮提供了一个很有前途的方法。
Zotero 插件