Philipps-Universität Marburg, Marburg, Germany.
University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA.
Cell Chem Biol. 2018 Jun 21;25(6):645-647. doi: 10.1016/j.chembiol.2018.06.003.
In this issue of Cell Chemical Biology, Pandey et al. (2018) identified that mitochondrial cysteine desulfurase provides the sulfur species used for tRNA, tRNA, and tRNA thiouridine modification in the cytoplasm. A low-mass sulfur species is exported by the mitochondrial Atm1 transporter and utilized in the thio-modifications.
在本期《细胞化学生物学》中，Pandey 等人（2018 年）发现线粒体半胱氨酸脱硫酸酶为细胞质中 tRNA、tRNA 和 tRNA 硫尿嘧啶修饰提供了所使用的硫物种。一种低质量的硫物种由线粒体 Atm1 转运蛋白输出，并用于硫修饰。
