Cui Yinglin, Zheng Weifeng, Xu Li, Meng Yi, Wang Yuqin, Chang Xuehui
J Tradit Chin Med. 2016 Oct;36(5):649-53. doi: 10.1016/s0254-6272(16)30085-1.
To analyze the distribution and combined regulation of elements of symptom patterns in the diagnosis of insomnia with Traditional Chinese Medicine (TCM).
The samples were collected from the patients, diagnosed with insomnia, of Henan Province Hospital of TCM between June 2011 and September 2013. The symptom patterns in insomnia were extracted. Next, symptom differentiation, characteristics of polysomnography (PSG), distribution and combined regulation of these symptom patterns were conducted by tests.
In total, 286 eligible patients were recruited. The main locations of the disease symptom elements were the brain and heart, and the main characteristics of the disease symptom elements were phlegm-heat, Yin-deficiency and Qi-stagnation. The elements from two or three symptom patterns were commonly manifested in patients with insomnia, especially from three symptom patterns. We also found that all TCM symptom patterns had an effect on polysomnographic indicators in PSG tests.
The elements of symptom patterns in insomnia were identified as mainly fire-heat and phlegm-heat. The most common patterns of excess were pathogenic fire derived from stagnation of liver- Qi, and mental disturbance due to phlegm-heat, while the most common patterns of deficiency in both the heart and the spleen. There are many differences in PSG indicators of different syndrome patterns of insomnia.
分析中医诊断失眠的症状要素分布及组合规律。
选取2011年6月至2013年9月河南省中医院失眠患者为样本,提取失眠症状要素,通过检验进行症状鉴别、多导睡眠图(PSG)特征、这些症状要素的分布及组合规律研究。
共纳入286例符合条件的患者。疾病症状要素主要病位在脑和心,主要病性为痰热、阴虚和气滞。失眠患者常见两证或三证要素组合,尤以三证要素组合多见。还发现所有中医证型在PSG检测中均对多导睡眠图指标有影响。
失眠症状要素以火热、痰热为主。实证以肝郁化火、痰热扰心最为常见,虚证以心脾两虚最为常见。不同证型失眠的PSG指标存在诸多差异。