Zou Chun-Cai, Yan Hai-Yan
Pharmacy School of Wannan Medical College, Wuhu 241002, China.
Zhongguo Zhong Yao Za Zhi. 2018 May;43(10):1969-1977. doi: 10.19540/j.cnki.cjcmm.20180115.018.
Over the past 30 years, the chromatographic fingerprint technology of traditional Chinese medicine (TCM) has been developed from academic discussion to application for the research and development of TCM which has promoted the technological innovation of Chinese medicine industry and the progress of quality standard of TCM. The similarity evaluation method of chromatographic fingerprint of TCM has played a key role in this process. According to the number of literature and research tendency in terms of the chromatographic fingerprint in the last 30 years, the chromatographic fingerprint evaluation could be divided into three stages: the direct comparison stage (1988-1999), similarity evaluation stage (2000-2009) and the similarity evaluation development stage (2010-2017). In this paper, the research progress of chromatographic fingerprints similarity evaluation of TCM in the last 30 years and its prospect were discussed, which may lead to a more mature stage for this method.
在过去30年里,中药色谱指纹图谱技术已从学术探讨发展到应用于中药研发,推动了中药产业的技术创新和中药质量标准的进步。中药色谱指纹图谱相似度评价方法在这一过程中发挥了关键作用。根据近30年色谱指纹图谱方面的文献数量和研究趋势,色谱指纹图谱评价可分为三个阶段:直接比较阶段(1988 - 1999年)、相似度评价阶段(2000 - 2009年)和相似度评价发展阶段(2010 - 2017年)。本文探讨了近30年中药色谱指纹图谱相似度评价的研究进展及其前景,这可能会使该方法进入一个更加成熟的阶段。