小鼠皮下纤维化的手法松动术
Manual Mobilization of Subcutaneous Fibrosis in Mice.
作者信息
Altomare Mariane, Monte-Alto-Costa Andréa
机构信息
Tissue Repair Laboratory, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Tissue Repair Laboratory, Rio de Janeiro State University, Rio de Janeiro, Brazil.
出版信息
J Manipulative Physiol Ther. 2018 Jun;41(5):359-362. doi: 10.1016/j.jmpt.2017.10.011. Epub 2018 Jun 20.
OBJECTIVE
The aim of this study was to induce the remodeling of subcutaneous fibrosis in mice by the manual mobilization of skin and subcutaneous tissue.
METHODS
Seven days after the induction of subcutaneous fibrosis, mice were divided into 3 groups: control, stretch, and manual mobilization. Stretch was achieved by elongating the trunk, and manual mobilization was achieved by using the indicator fingertip of both hands, side by side, touching the back and performing a brief stretch. Stretch or manual mobilization was performed once a day for 7 days.
RESULTS
Fibrosis was present in the subcutaneous tissue of control animals, whereas brief stretch and manual mobilization were found to reduce fibrosis.
CONCLUSIONS
Mechanical stimulation through manual mobilization, or brief stretching, reduced subcutaneous fibrosis after tissue injury.
目的
本研究的目的是通过手动移动皮肤和皮下组织来诱导小鼠皮下纤维化的重塑。
方法
皮下纤维化诱导7天后，将小鼠分为3组：对照组、拉伸组和手动移动组。通过拉长躯干实现拉伸，通过双手食指并排触摸背部并进行短暂拉伸实现手动移动。拉伸或手动移动每天进行1次，共进行7天。
结果
对照动物的皮下组织存在纤维化，而短暂拉伸和手动移动可减少纤维化。
结论
通过手动移动或短暂拉伸进行的机械刺激可减少组织损伤后的皮下纤维化。
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