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氧化型低密度脂蛋白和抗氧化型低密度脂蛋白抗体与动脉粥样硬化——诊断和治疗的新视角和未来方向<sup/>.

Oxidized LDL and anti-oxidized LDL antibodies in atherosclerosis - Novel insights and future directions in diagnosis and therapy<sup/>.

机构信息

National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom.

National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London W12 0NN, United Kingdom.

出版信息

Trends Cardiovasc Med. 2019 Jan;29(1):22-26. doi: 10.1016/j.tcm.2018.05.010. Epub 2018 Jun 4.

DOI:10.1016/j.tcm.2018.05.010
PMID:29934015
Abstract

We provide an up-to-date overview of current topics surrounding oxidized low-density lipoprotein (oxLDL) and its related antibodies in the quest to better identify the individuals at risk of cardiovascular disease and atherosclerotic plaques with unfavorable characteristics. We discuss the potential of oxLDL and anti-oxLDL antibodies as serum biomarkers of cardiovascular disease and emerging studies examining the targeting of arterial oxLDL for imaging and therapeutic delivery.

摘要

我们提供了关于氧化型低密度脂蛋白（oxLDL）及其相关抗体的最新综述，旨在更好地识别心血管疾病和具有不利特征的动脉粥样硬化斑块风险人群。我们讨论了 oxLDL 和抗 oxLDL 抗体作为心血管疾病血清生物标志物的潜力，以及正在研究的针对动脉 oxLDL 的成像和治疗性递药的新方法。

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Oxidized LDL and anti-oxidized LDL antibodies in atherosclerosis - Novel insights and future directions in diagnosis and therapy<sup/>.氧化型低密度脂蛋白和抗氧化型低密度脂蛋白抗体与动脉粥样硬化——诊断和治疗的新视角和未来方向<sup/>.
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