Los Alamos National Laboratory, Center for Integrated Nanotechnologies, Materials Physics and Applications Division (MPA-CINT), Los Alamos, NM, 87545, USA.
Los Alamos National Laboratory, Institute for Materials Science (IMS), Los Alamos, NM, 87545, USA.
J Biol Inorg Chem. 2018 Oct;23(7):1153-1157. doi: 10.1007/s00775-018-1580-6. Epub 2018 Jun 22.
An optically active metallo-polymer assembly is demonstrated via conjugation of a genetically engineered elastin-like polypeptide (ELP) and a ruthenium(II) polypyridyl complex. By taking advantage of the phase transition of ELPs in water, photophysical properties of the resultant conjugate are investigated for both phases, below and above the critical transition temperature. Upon coacervation, the luminescence of the metallo-ELP is greatly enhanced as a consequence of local effects on the metal-ligand luminophore. These findings open a possibility to harness the temperature control of stimuli-responsive properties of biopolymers.
通过将基因工程弹性蛋白样多肽 (ELP) 和钌 (II) 多吡啶配合物进行偶联，展示了一种具有光活性的金属聚合物组装体。通过利用 ELPs 在水中的相转变，研究了所得共轭物在临界转变温度以下和以上两种相态下的光物理性质。共凝聚后，由于金属配体发光体的局部效应，金属-ELP 的发光大大增强。这些发现为利用生物聚合物对刺激响应性质的温度控制提供了可能性。
