Baotou Medical College, Baotou 014060, Inner Mongolia, China.
Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plants, Nanning, Guangxi 530023, China.
J Ethnopharmacol. 2018 Oct 28;225:18-30. doi: 10.1016/j.jep.2018.06.029. Epub 2018 Jun 20.
The genus Salvia is one of the largest genera of the Lamiaceae family. In China, about 40 Salvia species have been used as medicinal plants for treatment of various diseases, specifically hepatic and renal diseases and those of the cardiovascular and immune systems.
This review aims to provide systematically organized information on the ethnopharmacology, phytochemistry, pharmacology, and toxicology of medicinal Salvia species in China to support their therapeutic potential in the treatment of human diseases.
Relevant information on the Chinese Salvia species was obtained from scientific online databases such as Google Scholar, PubMed, and SciFinder. Additional information was derived from other literature sources (e.g. Chinese Pharmacopoeia 2015 edition, Chinese herbal classic books, PhD and MSc thesis, etc).
Our comprehensive analysis of the scientific literature indicates that many Chinese Salvia species are valuable and popular herbal medicines with therapeutic potentials to cure various ailments. Phytochemical analyses identified diterpenoids and phenolic acids as the major bioactive substances in Chinese Salvia species. Crude extracts and pure compounds isolated from the Chinese Salvia species exhibited various pharmacological activities, typically targeting the cardiovascular and immune systems and hepatic and renal diseases.
This review summarizes the results from current studies about basic properties of medicinal Salvia species in China, such as active constituents and their mechanism of action, pharmacokinetics, underlying molecular mechanisms, toxicology, and efficacy, which are still being studied and explored to achieve integration into medical practice.
鼠尾草属是唇形科最大的属之一。在中国，约有 40 种鼠尾草被用作药用植物，用于治疗各种疾病，特别是肝脏和肾脏疾病以及心血管和免疫系统疾病。
本综述旨在提供中国药用鼠尾草属植物的民族药理学、植物化学、药理学和毒理学方面的系统信息，以支持其在治疗人类疾病方面的治疗潜力。
从 Google Scholar、PubMed 和 SciFinder 等科学在线数据库中获取有关中国鼠尾草属植物的相关信息。其他文献来源（如 2015 年版《中国药典》、中草药经典书籍、博士和硕士论文等）也提供了额外的信息。
我们对科学文献的综合分析表明，许多中国鼠尾草属植物是具有治疗潜力的有价值的常用草药，可以治疗各种疾病。植物化学分析确定二萜类化合物和酚酸类化合物是中国鼠尾草属植物中的主要生物活性物质。从中国鼠尾草属植物中分离得到的粗提取物和纯化合物表现出多种药理活性，主要针对心血管和免疫系统以及肝脏和肾脏疾病。
本综述总结了关于中国药用鼠尾草属植物基本特性的当前研究结果，如活性成分及其作用机制、药代动力学、潜在分子机制、毒理学和疗效等，这些仍在研究和探索中，以实现整合到医疗实践中。
