Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University School of Public Health, Graduate School of Medicine, Sendai, Japan; Child and Adolescent Psychiatry, Miyagi Psychiatric Center, Natori, Japan.
Division of Epidemiology, Department of Health Informatics and Public Health, Tohoku University School of Public Health, Graduate School of Medicine, Sendai, Japan.
J Psychosom Res. 2018 Aug;111:36-41. doi: 10.1016/j.jpsychores.2018.05.004. Epub 2018 May 9.
Although several longitudinal studies have examined the relationship between social participation and incident functional disability, the related mechanisms have remained unclear. The aim of this study was to examine the mechanisms linking social participation to incident functional disability.
We analyzed follow-up data for 11,992 older adults (≥65 years) participating in a community-based, prospective cohort study covering a 9-year period. At the baseline, the subjects were asked about three types of participation in community activities (volunteering, hobbies, and neighborhood associations) and the frequency of their participation. Data on incident functional disability were retrieved from the public Long-term Care Insurance database. The Cox model was used to estimate the multivariate-adjusted hazard ratios of incident functional disability. We then conducted mediation analysis to assess the magnitude of the mediating effect.
Among 84,760 person-years of follow-up, there were 3,984 cases of incident functional disability. The hazard ratio was 0.79 (95% CI: 0.73-0.86) for participating in one type of activity, 0.82 (95% CI: 0.74-0.90) for two types of activity and 0.70 (95% CI: 0.64-0.77) for three types of activity in comparison with no participation in any activity. Among the estimated mediating effects, cognitive activity accounted for 9.3%, time spent walking for 8.3%, psychological state for 4.6%, and social support for 2.8% of the reduced risk of incident functional disability.
The results of this population-based cohort study indicate that cognitive activity and time spent walking are important mechanisms linking social participation to incident functional disability.
尽管有几项纵向研究考察了社会参与和功能障碍事件之间的关系,但相关机制仍不清楚。本研究旨在探讨社会参与与功能障碍事件之间的关联机制。
我们分析了一项为期 9 年的社区为基础的前瞻性队列研究中 11992 名年龄在 65 岁及以上的老年人的随访数据。在基线时,要求受试者报告三种类型的社区活动参与情况(志愿活动、爱好和邻里协会)以及参与频率。功能障碍事件的数据从公共长期护理保险数据库中获取。使用 Cox 模型估计功能障碍事件的多变量调整后危险比。然后进行中介分析以评估中介效应的大小。
在 84760 人年的随访期间,有 3984 例功能障碍事件。与不参与任何活动相比,参与一种活动的危险比为 0.79(95%CI:0.73-0.86),参与两种活动的危险比为 0.82(95%CI:0.74-0.90),参与三种活动的危险比为 0.70(95%CI:0.64-0.77)。在估计的中介效应中,认知活动占功能障碍事件风险降低的 9.3%,散步时间占 8.3%,心理状态占 4.6%,社会支持占 2.8%。
这项基于人群的队列研究结果表明,认知活动和散步时间是社会参与与功能障碍事件之间关联的重要机制。