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女性腹主动脉瘤中同步和异时性动脉瘤的患病率。

Prevalence of Synchronous and Metachronous Aneurysms in Women With Abdominal Aortic Aneurysm.

机构信息

Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden; Department of Surgery, Sundsvall District Hospital, Sundsvall, Sweden.

Department of Surgical Sciences, Section of Vascular Surgery, Uppsala University, Uppsala, Sweden.

出版信息

Eur J Vasc Endovasc Surg. 2018 Sep;56(3):435-440. doi: 10.1016/j.ejvs.2018.05.015. Epub 2018 Jun 20.

Abstract

BACKGROUND

Abdominal aortic aneurysm (AAA) is three to five times more common among men compared with women, yet up to 38% of all aneurysm related deaths affect women. The aim of this study was to estimate the prevalence of synchronous or metachronous aneurysms among women with AAA, as diagnosis and treatment could improve survival.

PATIENTS AND METHODS

This is a retrospective study of prospectively registered patients. All women operated on, or under surveillance for, AAA were identified at two Swedish hospitals. Aneurysms in different locations were identified using available imaging studies. Aneurysms were defined according to location: thoracic ascending aorta ≥42 mm, descending ≥33 mm, abdominal aorta ≥30 mm, common iliac artery ≥20 mm or 50% wider than the contralateral artery, common femoral artery ≥12 mm, popliteal artery ≥10 mm.

RESULTS

A total of 339 women with an AAA were included. The median follow up was 2.8 (range 0-15.7) years. Thirty-one per cent had an aneurysm in the thoracic aorta (67 of 217 investigated, 84% were located in the descending aorta), 13 (19%) underwent repair. Twelve per cent had a common iliac artery aneurysm (24/259, 76% were investigated). Common femoral artery aneurysms were identified in 4.3% (8/184, 54% investigated). Popliteal artery aneurysms were identified in 4.0% (6/149, 44% investigated). The prevalence of infrainguinal aneurysms was higher among patients with synchronous iliac aneurysms (40% vs. 1.6%, OR 42, 95% CI 6.4-279, p < .001).

CONCLUSIONS

Thoracic aortic aneurysms are common among women with AAA, most commonly affecting the descending aorta, and detection frequently results in repair. Popliteal and femoral aneurysms are not rare among women with AAA, and even common if there is a synchronous iliac aneurysm.

摘要

背景

与女性相比,男性的腹主动脉瘤(AAA)发病率高出三到五倍,但高达 38%的所有与动脉瘤相关的死亡都发生在女性身上。本研究的目的是评估女性 AAA 患者同时或异时性动脉瘤的患病率,因为诊断和治疗可能会提高生存率。

患者和方法

这是一项在瑞典两家医院进行的前瞻性注册患者的回顾性研究。通过可用的影像学研究确定在这两家医院接受手术或接受 AAA 监测的所有女性患者。使用可用的影像学研究确定不同部位的动脉瘤。根据位置定义动脉瘤:胸主动脉升部≥42mm,降部≥33mm,腹主动脉≥30mm,髂总动脉≥20mm 或比对侧动脉宽 50%,股总动脉≥12mm,腘动脉≥10mm。

结果

共纳入 339 名患有 AAA 的女性患者。中位随访时间为 2.8 年(范围 0-15.7 年)。31%的患者有胸主动脉瘤(217 例中 67 例,84%位于降主动脉),其中 13 例(19%)接受了修复。12%的患者有髂总动脉动脉瘤(259 例中 24 例,76%进行了检查)。股总动脉动脉瘤的检出率为 4.3%(184 例中 8 例,54%进行了检查)。腘动脉动脉瘤的检出率为 4.0%(149 例中 6 例,44%进行了检查)。有同时性髂动脉瘤的患者中, infrainguinal 动脉瘤的患病率更高(40%比 1.6%,OR 42,95%CI 6.4-279,p<0.001)。

结论

女性 AAA 患者中常见胸主动脉瘤,最常见于降主动脉,且常因发现而进行修复。女性 AAA 患者中腘动脉和股动脉动脉瘤并不罕见,如果同时存在髂动脉瘤则更为常见。

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