Zhang Ying, Kishi Hiroko, Kobayashi Sei
Department of Molecular and Cellular Physiology, Yamaguchi University, Graduate School of Medicine, 1-1-1 Minami-kogushi, Ube, 755-8505, Japan.
Department of Molecular and Cellular Physiology, Yamaguchi University, Graduate School of Medicine, 1-1-1 Minami-kogushi, Ube, 755-8505, Japan.
Pharmacol Res. 2018 Aug;134:200-211. doi: 10.1016/j.phrs.2018.06.004. Epub 2018 Jun 21.
Add-on therapy with traditional Chinese medicine (TCM) has been extensively researched in the intractable diseases, such as asthma, cancer, and Alzheimer's disease. As an entirely new concept, add-on therapy of TCM has been also used to prevent and treat hyperlipidemia via lowering cholesterol level. However, the efficacy of add-on therapy with TCM for mediating lipid metabolism disorders remains controversial. In this review, we summarize and provide strong evidence that add-on therapy of TCM as a novel approach is efficacious and safe for hyperlipidemia associated diseases based on the mediation of lipid metabolism disorders.
中药辅助疗法已在哮喘、癌症和阿尔茨海默病等难治性疾病中得到广泛研究。作为一个全新的概念，中药辅助疗法也被用于通过降低胆固醇水平来预防和治疗高脂血症。然而，中药辅助疗法对调节脂质代谢紊乱的疗效仍存在争议。在本综述中，我们总结并提供了有力证据，表明基于脂质代谢紊乱的调节，中药辅助疗法作为一种新方法对高脂血症相关疾病是有效且安全的。
