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Oman Med J. 2024 Nov 30;39(6):e699. doi: 10.5001/omj.2024.35. eCollection 2024 Nov.

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1
Heterotopic Pancreas of the Gastrointestinal Tract and Associated Precursor and Cancerous Lesions: Systematic Pathologic Studies of 165 Cases.胃肠道异位胰腺及相关前驱和癌性病变：165例系统病理研究
Am J Surg Pathol. 2017 Jun;41(6):833-848. doi: 10.1097/PAS.0000000000000850.
2
The Evolving Role of Pathology in New Developments, Classification, Terminology, and Diagnosis of Pancreatobiliary Neoplasms.病理学在胰胆肿瘤新进展、分类、术语及诊断中的角色演变
Arch Pathol Lab Med. 2017 Mar;141(3):366-380. doi: 10.5858/arpa.2016-0262-SA. Epub 2017 Jan 5.
3
Pathology of Pancreatic Cancer Precursor Lesions.胰腺癌前驱病变的病理学
Surg Pathol Clin. 2016 Dec;9(4):561-580. doi: 10.1016/j.path.2016.05.004. Epub 2016 Oct 12.
4
Heterotopic pancreatic rests: imaging features, complications, and unifying concepts.异位胰腺遗迹：影像学特征、并发症及统一概念。
Abdom Radiol (NY). 2017 Jan;42(1):216-225. doi: 10.1007/s00261-016-0874-9.
5
Cytological findings of an ectopic pancreas of the stomach obtained at endoscopic ultrasound-guided fine needle aspiration, differential diagnosis from acinar cell carcinoma: a case report.内镜超声引导下细针穿刺获取的胃异位胰腺的细胞学检查结果，与腺泡细胞癌的鉴别诊断：病例报告
Cytopathology. 2016 Oct;27(5):379-81. doi: 10.1111/cyt.12302. Epub 2016 Jan 20.
6
Pancreatic intraepithelial neoplasia arising from an ectopic pancreas in the small bowel.起源于小肠异位胰腺的胰腺上皮内瘤变。
Hepatobiliary Pancreat Dis Int. 2014 Dec;13(6):658-61. doi: 10.1016/s1499-3872(14)60273-3.
7
Therapeutic outcomes of endoscopic resection for superficial non-ampullary duodenal tumor.内镜切除治疗非壶腹性十二指肠浅表肿瘤的疗效。
Dig Endosc. 2014 Apr;26 Suppl 2:50-6. doi: 10.1111/den.12273.
8
Premalignant lesion of heterotopic pancreas combined with gastritis cystica profunda in gastric fundus.胃底部异位胰腺伴先天性胃底腺囊肿的癌前病变。
J Gastrointestin Liver Dis. 2013 Sep;22(3):337-40.
9
Heterotopic pancreas in the stomach: a case report and a brief review of the literature.胃内异位胰腺：一例报告并文献简要综述
JOP. 2010 May 5;11(3):255-7.
10
Malignant transformation of ectopic pancreatic cells in the duodenal wall.十二指肠壁异位胰腺细胞的恶性转化。
World J Gastroenterol. 2010 Mar 14;16(10):1293-5. doi: 10.3748/wjg.v16.i10.1293.

异位胰腺中的胰腺上皮内瘤变：在十二指肠息肉内镜黏膜切除术中偶然诊断出。

Pancreatic intraepithelial neoplasia in heterotopic pancreas: incidentally diagnosed on endoscopic mucosal resection of a duodenal polyp.

作者信息

Safadi Sarah, Martin David R, Rustagi Tarun

机构信息

Department of Internal Medicine, University of New Mexico Hospital, Albuquerque, New Mexico, USA.

Department of Pathology, University of New Mexico Hospital, Albuquerque, New Mexico, USA.

出版信息

BMJ Case Rep. 2018 Jun 23;2018:bcr-2018-224414. doi: 10.1136/bcr-2018-224414.

DOI:10.1136/bcr-2018-224414
PMID:29936443
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6020903/
Abstract

Heterotopic pancreas is the presence of pancreatic tissue outside its normal location. It can develop similar pathological conditions that develop in the normal pancreas, including adenocarcinoma and its precursor lesions. Due to the rarity of the condition, the diagnosis can be challenging, and treatment is not well established. ​We present a 47-year-old female patient referred for endoscopic resection of a 2 cm polyp in the second part of her duodenum. Complete endoscopic mucosal resection (EMR) was performed, with pathology revealing low-grade pancreatic intraepithelial neoplasia (PanIN) in heterotopic pancreatic tissue. To the best of our knowledge, this is the first case of heterotopic pancreas with low-grade PanIN in the duodenum to be incidentally diagnosed and treated with EMR.

摘要

异位胰腺是指胰腺组织出现在其正常位置以外的地方。它可发生与正常胰腺相似的病理状况，包括腺癌及其前驱病变。由于该病症罕见，诊断具有挑战性，且治疗方法尚未明确。我们报告一名47岁女性患者，因十二指肠第二部有一个2厘米的息肉而前来接受内镜切除。进行了完整的内镜黏膜切除术（EMR），病理检查显示异位胰腺组织中有低级别胰腺上皮内瘤变（PanIN）。据我们所知，这是首例十二指肠异位胰腺伴低级别PanIN经偶然诊断并接受EMR治疗的病例。