Macedo Francisco Igor, Taggarshe Deepa, Makarawo Tafadzwa, Herschman Barry, Jacobs Michael J
Department of General Surgery, Providence Hospital and Medical Centers, Southfield, MI 48075, USA.
Hepatobiliary Pancreat Dis Int. 2014 Dec;13(6):658-61. doi: 10.1016/s1499-3872(14)60273-3.
Ectopic pancreatic tissue is relatively uncommon, and is characterized as pancreatic tissue with no contact with the normal pancreas, and with its own ductal system and blood supply. It is usually asymptomatic, and can be incidentally diagnosed by conventional imaging studies.
A 69-year-old woman with a prior history of bilateral breast carcinoma presented with ectopic pancreatic intraepithelial neoplasia (PanIN) that was identified incidentally in the small bowel during an oncological resection of a synchronous primary pancreatic adenocarcinoma, and renal cell carcinoma.
The patient underwent subtotal pancreatectomy with splenectomy, regional lymphadenectomy, radical left nephrectomy, and small bowel resection with primary anastomosis of ectopic PanIN-2. She had an uneventful hospitalization and was discharged home on postoperative day 7.
The occurrence of ectopic PanIN is extremely unusual with only few cases previously reported in the literature. The need for negative margins after surgical resection of ectopic PanIN lesions remains controversial.
异位胰腺组织相对少见，其特征为与正常胰腺无连接，且有自身的导管系统和血供。它通常无症状，可通过传统影像学检查偶然发现。
一名69岁有双侧乳腺癌病史的女性，在同步原发性胰腺腺癌及肾细胞癌的肿瘤切除术中，于小肠偶然发现异位胰腺上皮内瘤变（PanIN）。
患者接受了胰腺次全切除术加脾切除术、区域淋巴结清扫术、根治性左肾切除术以及异位PanIN-2小肠切除术并一期吻合。她住院过程顺利，术后第7天出院。
异位PanIN的发生极为罕见，此前文献仅报道过少数病例。异位PanIN病变手术切除后切缘阴性的必要性仍存在争议。
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