作者对赖思的回复：“与病态肥胖成年人相比，肥胖青少年咪达唑仑清除率更高” 。 - Suppr

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超能文献

Author's Reply to Reith: "Higher Midazolam Clearance in Obese Adolescents Compared with Morbidly Obese Adults".

作者信息

van Rongen Anne, van den Anker Johannes N, Knibbe Catherijne A J

机构信息

Department of Clinical Pharmacy, Reinier de Graaf Hospital, Delft, The Netherlands.

Intensive Care and Department of Pediatric Surgery, Erasmus MC Sophia Children's Hospital, Rotterdam, The Netherlands.

出版信息

Clin Pharmacokinet. 2018 Oct;57(10):1357-1358. doi: 10.1007/s40262-018-0692-z.

DOI:10.1007/s40262-018-0692-z

PMID:29936679

Abstract

摘要

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Author's Reply to Reith: "Higher Midazolam Clearance in Obese Adolescents Compared with Morbidly Obese Adults".作者对赖思的回复：“与病态肥胖成年人相比，肥胖青少年咪达唑仑清除率更高” 。

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本文引用的文献

Higher Midazolam Clearance in Obese Adolescents Compared with Morbidly Obese Adults.肥胖青少年咪达唑仑清除率高于病态肥胖成年人。

Clin Pharmacokinet. 2018 May;57(5):601-611. doi: 10.1007/s40262-017-0579-4.

Changes in duration of action of rocuronium following decrease in hepatic blood flow during pneumoperitoneum for laparoscopic gynaecological surgery.腹腔镜妇科手术气腹期间肝血流减少后罗库溴铵作用持续时间的变化

BMC Anesthesiol. 2017 Mar 20;17(1):45. doi: 10.1186/s12871-017-0335-1.

The Pharmacokinetics of the CYP3A Substrate Midazolam in Morbidly Obese Patients Before and One Year After Bariatric Surgery.CYP3A底物咪达唑仑在病态肥胖患者减肥手术前及术后一年的药代动力学

Pharm Res. 2015 Dec;32(12):3927-36. doi: 10.1007/s11095-015-1752-9. Epub 2015 Jul 23.

Midazolam pharmacokinetics in morbidly obese patients following semi-simultaneous oral and intravenous administration: a comparison with healthy volunteers.病态肥胖患者口服与静脉半同步给药后咪达唑仑的药代动力学：与健康志愿者的比较

Clin Pharmacokinet. 2014 Oct;53(10):931-41. doi: 10.1007/s40262-014-0166-x.

Effects of oral clotrimazole troches on the pharmacokinetics of oral and intravenous midazolam.克霉唑口含片对口服和静脉注射咪达唑仑药代动力学的影响。

Br J Clin Pharmacol. 2010 Feb;69(2):160-6. doi: 10.1111/j.1365-2125.2009.03559.x.

Application of semisimultaneous midazolam administration for hepatic and intestinal cytochrome P450 3A phenotyping.半同步给予咪达唑仑在肝脏和肠道细胞色素P450 3A表型分析中的应用。

Clin Pharmacol Ther. 2002 Dec;72(6):718-28. doi: 10.1067/mcp.2002.129068.

Integrated pharmacokinetics and pharmacodynamics of Ro 48-8684, a new benzodiazepine, in comparison with midazolam during first administration to healthy male subjects.新型苯二氮䓬类药物Ro 48 - 8684与咪达唑仑在首次给药于健康男性受试者时的药代动力学和药效学整合比较。

Br J Clin Pharmacol. 1997 Nov;44(5):487-93. doi: 10.1046/j.1365-2125.1997.t01-1-00613.x.

Oral first-pass elimination of midazolam involves both gastrointestinal and hepatic CYP3A-mediated metabolism.咪达唑仑的口服首过消除涉及胃肠道和肝脏中细胞色素P450 3A（CYP3A）介导的代谢。

Clin Pharmacol Ther. 1996 May;59(5):491-502. doi: 10.1016/S0009-9236(96)90177-0.

Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily.人细胞色素P450 3A（CYP3A）亚家族成员对咪达唑仑的区域选择性生物转化。

Biochem Pharmacol. 1994 Apr 29;47(9):1643-53. doi: 10.1016/0006-2952(94)90543-6.

Effect of age, gender, and obesity on midazolam kinetics.年龄、性别和肥胖对咪达唑仑动力学的影响。

Anesthesiology. 1984 Jul;61(1):27-35.

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