Yin Z X, Ren Z P, Xu X G, Zhang J, Wang Z Q, Zhang M, Zhai Y, Song P K, Zhao Y F, Pang S J, Mi S Q, Zhao W H
Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Shanxi Provincial Center for Disease Control and Prevention, Taiyuan 030012, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Jun 10;39(6):781-785. doi: 10.3760/cma.j.issn.0254-6450.2018.06.017.
To study the association between blood pressure related dietary pattern and cognitive impairment in the elderly. In 2015, all participants who were aged ≥60 and participated in the Nutrition and Chronic disease family cohort were involved in the study. Information on demographic variables, lifestyle and health status was collected. Cognitive performance was assessed by the Mini Mental State Evaluation (MMSE) scale. Blood pressure, height and weight were measured by trained medical personnel and fasting venous blood samples were collected for testing on serum level of triglycerides and total cholesterol. Both SBP and DBP were used as response variables when dietary patterns were identified by reduced rank regression method. Logistic regression models were fit to explore the associations of scores on blood pressure-related dietary pattern and cognitive impairment. Two blood related dietary patterns were identified. The first one was characterized by high consumption of vegetables and less meat, eggs and dessert (Pattern 1), while the second one was with high consumption of meat, soy products, wine and fried foods and less intake of dairy (Pattern 2). Data showed that the Pattern 1 was associated with the risk of cognitive impairment. Comparing with the lowest quartile of score of this dietary pattern, the risk of cognitive impairment in the highest quartile group showed a significant (<0.01) increase, with =1.94 (1.21-3.11) and showing significant (=0.002) linear trend. However, no significant association was observed (>0.05) with cognitive impairment in the second dietary pattern. Blood pressure-related dietary pattern was positively associated with cognitive impairment.
研究老年人血压相关饮食模式与认知障碍之间的关联。2015年,所有年龄≥60岁且参与营养与慢性病家庭队列研究的参与者均纳入本研究。收集了人口统计学变量、生活方式和健康状况等信息。认知功能通过简易精神状态检查表(MMSE)进行评估。血压、身高和体重由经过培训的医务人员测量,并采集空腹静脉血样本检测甘油三酯和总胆固醇的血清水平。当采用降秩回归法确定饮食模式时,收缩压(SBP)和舒张压(DBP)均用作反应变量。采用逻辑回归模型探讨血压相关饮食模式得分与认知障碍之间的关联。确定了两种与血液相关的饮食模式。第一种以高蔬菜摄入量、低肉类、蛋类和甜点摄入量为特征(模式1),而第二种以高肉类、豆制品、酒类和油炸食品摄入量、低乳制品摄入量为特征(模式2)。数据显示,模式1与认知障碍风险相关。与该饮食模式得分最低的四分位数组相比,得分最高的四分位数组认知障碍风险显著(<0.01)增加,比值比为1.94(1.21 - 3.11),且呈显著(=0.002)线性趋势。然而,未观察到第二种饮食模式与认知障碍有显著关联(>0.05)。血压相关饮食模式与认知障碍呈正相关。