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用于下颌骨重建的低成本自制计算机辅助设计/计算机辅助制造导向系统。

Low-cost, self-made CAD/CAM-guiding system for mandibular reconstruction.

作者信息

Dell'Aversana Orabona Giovanni, Abbate Vincenzo, Maglitto Fabio, Bonavolontà Paola, Salzano Giovanni, Romano Antonio, Reccia Alfonso, Committeri Umberto, Iaconetta Giorgio, Califano Luigi

机构信息

Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Federico II, Via Pansini 5, 80100 Naples, Italy.

Maxillofacial Surgery Unit, Department of Neurosciences, Reproductive and Odontostomatological Sciences, University Federico II, Via Pansini 5, 80100 Naples, Italy.

出版信息

Surg Oncol. 2018 Jun;27(2):200-207. doi: 10.1016/j.suronc.2018.03.007. Epub 2018 Mar 29.

DOI:10.1016/j.suronc.2018.03.007
PMID:29937172
Abstract

Facial symmetry, as well as function, remains the big challenge for surgeons who attempt mandibular reconstruction. Nowadays several studies recommend the use of computer aided surgery (CAS) and CAD/CAM technology to guide mandibular segmental osteotomies and reconstruction using free fibula flap. Although these systems have radically changed the way of doing mandibular reconstructive surgery, they are expensive and require extended periods of time for prototypation. This may be an important limitation in case of malignant neoplasms which require short-term treatment. The aim of our study is to investigate the reliability and efficiency of a protocol to obtain cutting guides produced in a "homemade" way. This study includes four consecutive patients who underwent a segmental mandibulectomy and fibula osteo-cutaneous free flap reconstruction for oral squamous cell carcinoma between January and September 2016. The CAD/CAM system algorithm proposed was based on the use of free open source software for digital planning and 3D layer plastic deposition printer. A cost of about 3 Euro for each case was estimated. An average mean distance between 3D preoperative and postoperative mesh points of 1.631 mm and a standard deviation of 5.496 mm has been demonstrated by 3D volume overlay analysis. Overlapping results with much shorter prototyping time was required with the in-house procedure described as compared to the available commercial system. In conclusion, we expect that this technique will reduce operative time and cost however further study and large series are needed to confirm our results and better define the applicability in everyday surgical practice.

摘要

面部对称性以及功能,对于尝试进行下颌骨重建的外科医生来说仍然是巨大的挑战。如今,多项研究推荐使用计算机辅助手术(CAS)和CAD/CAM技术来指导下颌骨节段性截骨术以及使用游离腓骨瓣进行重建。尽管这些系统已经从根本上改变了下颌骨重建手术的方式,但它们价格昂贵,并且原型制作需要很长时间。对于需要短期治疗的恶性肿瘤患者而言,这可能是一个重要的限制因素。我们研究的目的是调查一种以“自制”方式获取切割导板的方案的可靠性和效率。本研究纳入了2016年1月至9月期间连续4例因口腔鳞状细胞癌接受节段性下颌骨切除术和腓骨骨皮游离瓣重建术的患者。所提出的CAD/CAM系统算法基于使用免费开源软件进行数字规划以及3D分层塑料沉积打印机。估计每例的成本约为3欧元。通过3D体积叠加分析显示,术前和术后3D网格点之间的平均距离为1.631毫米,标准差为5.496毫米。与现有的商业系统相比,所描述的内部程序需要更短的原型制作时间且结果重叠。总之,我们期望这种技术将减少手术时间和成本,然而还需要进一步的研究和大量病例系列来证实我们的结果,并更好地确定其在日常外科实践中的适用性。

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