小型猪的前庭诱发肌源性电位
Vestibular-evoked myogenic potentials in miniature pigs.
作者信息
Shi Xi, Zhang Yan, Li Ya, Qiu Shiwei, Zhang Shili, Li Yaohan, Yuan Na, Qiao Yuehua, Yang Shiming
机构信息
Institute of Audiology and Balance Science, Xuzhou Medical University, China.
Department of Otorhinolaryngology Head and Neck Surgery, First Hospital of Jilin University, Changchun, Jilin 130021, China.
出版信息
J Otol. 2016 Jun;11(2):88-93. doi: 10.1016/j.joto.2016.05.003. Epub 2016 Jun 10.
OBJECTIVE
To report detection of vestibular-evoked myogenic potentials (VEMPs) in the miniature pig.
METHODS
Potentials evoked by 1000 Hz tone bursts were recorded from neck extensor muscles and the masseter muscles in normal adult Bama miniature pigs anesthetized with 3% pentobarbital sodium and Carbachol II.
RESULTS
The latency of the first positive wave P from neck extensor muscles was 7.65 ± 0.64 ms, with an amplitude of 1.66 ± 0.34 uv and a rate of successful induction of 75% at 80 dB SPL. The latency of potentials evoked from the masseter muscles was 7.60 ± 0.78 ms, with an amplitude of 1.31 ± 0.28 uv and a rate successful induction of 66% at 80 dB SPL.
CONCLUSION
The latencies and thresholds of VEMPs recorded from the neck extensor muscle and the masseter muscle appear to be comparable in normal adult Bama miniature pigs, although the amplitude recorded from the neck extensor muscle seems to be higher than that from the masseter muscle. However, because of their usually relatively superficial and easily accessible location, as well as their large volume and strong contractions, masseter muscles may be better target muscles for recording myogenic potentials.
目的
报告小型猪前庭诱发肌源性电位（VEMPs）的检测情况。
方法
在使用3%戊巴比妥钠和卡巴胆碱II麻醉的正常成年巴马小型猪中，从颈部伸肌和咬肌记录1000Hz短纯音诱发的电位。
结果
颈部伸肌第一个正向波P的潜伏期为7.65±0.64毫秒，波幅为1.66±0.34微伏，在80dB SPL时成功诱发率为75%。咬肌诱发电位的潜伏期为7.60±0.78毫秒，波幅为1.31±0.28微伏，在80dB SPL时成功诱发率为66%。
结论
在正常成年巴马小型猪中，从颈部伸肌和咬肌记录的VEMPs的潜伏期和阈值似乎相当，尽管从颈部伸肌记录的波幅似乎高于咬肌。然而，由于咬肌通常位置相对表浅且易于触及，以及其体积大、收缩力强，咬肌可能是记录肌源性电位更好的目标肌肉。
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