[健康豚鼠的前庭诱发肌源性电位]
[Vestibular-evoked myogenic potentials in healthy guinea pigs].
作者信息
Chen Z C, Zhang Y Z, Yang Y Z, Wei X Y, Hu J, Gao Y, Chen F Y, Luo H N, Xu M, Zhang Q
机构信息
Department of Otorhinolaryngology Head and Neck Surgery, the Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710004, China.
Department of Otolaryngology, Shangluo District People's Hospital.
出版信息
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Aug;32(16):1265-1270. doi: 10.13201/j.issn.1001-1781.2018.16.013.
To establish detection methods of air-conducted sound elicited vestibular-evoked myogenic potentials (ACS-VEMPs) in guinea pigs, including cervical vstibular-evoked myogenic potential (cVEMP) and ocular vestibular evoked myogenic potential (oVEMP). Eleven healthy (250-350 g) guinea pigs (22 ears) were selected and underwent conventional ACS-cVEMP and ACS-oVEMP examinations. Parameters of waveforms were recorded. The ACS-cVEMP and ACS-oVEMP could be elicited in 77.27% and 59.09% guinea pigs,respectively；threshold was (107.1±14.6)dB SPL and (115.5±15.6)dB SPL for ACS-cVEMP and ACS-oVEMP；n1,p1 latency for cVEMP was (7.4±1.5)ms and (9.3±1.6)ms，(6.4±1.4)ms and (8.1±1.8)ms for oVEMP；amlipude was (15.4±8.6)μV and (11.4±6.0)μV for cVEMP and oVEMP respectively. No statistical difference could be found in above parameters between ACS-cVEMP and ACS-oVEMP (>0.05). Both ACS-cVEMP and ACS-oVEMP could be elicited in guinea pigs.
建立豚鼠气导声诱发前庭肌源性电位（ACS-VEMPs）的检测方法，包括颈前庭肌源性电位（cVEMP）和眼前庭肌源性电位（oVEMP）。选取11只健康（250 - 350 g）豚鼠（22耳），进行常规的ACS-cVEMP和ACS-oVEMP检查。记录波形参数。ACS-cVEMP和ACS-oVEMP在豚鼠中的引出率分别为77.27%和59.09%；ACS-cVEMP和ACS-oVEMP的阈值分别为（107.1±14.6）dB SPL和（115.5±15.6）dB SPL；cVEMP的n1、p1潜伏期分别为（7.4±1.5）ms和（9.3±1.6）ms，oVEMP的为（6.4±1.4）ms和（8.1±1.8）ms；cVEMP和oVEMP的波幅分别为（15.4±8.6）μV和（11.4±6.0）μV。ACS-cVEMP和ACS-oVEMP上述参数之间差异无统计学意义（P>0.05）。豚鼠可引出ACS-cVEMP和ACS-oVEMP。
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