Hentzen Judith E K R, de Jongh Steven J, Hemmer Patrick H J, van der Plas Willemijn Y, van Dam Gooitzen M, Kruijff Schelto
Department of Surgery, Division of Surgical Oncology, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands.
Department of Gastroenterology and Hepatology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.
J Surg Oncol. 2018 Aug;118(2):332-343. doi: 10.1002/jso.25106. Epub 2018 Jun 24.
Patients with peritoneal carcinomatosis (PC) from colorectal origin may undergo cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) as a curative approach. One major prognostic factor that affects survival is completeness of cytoreduction. Molecular Fluorescence Guided Surgery (MFGS) is a novel intraoperative imaging technique that may improve tumor identification in the future, potentially preventing over- and under-treatment in these patients. This narrative review outlines a chronological overview of MFGS development in patients with PC of colorectal origin.
来自结直肠原发的腹膜癌转移（PC）患者可能接受细胞减灭术（CRS）联合腹腔内热灌注化疗（HIPEC）作为一种治愈性方法。影响生存的一个主要预后因素是细胞减灭的彻底性。分子荧光引导手术（MFGS）是一种新型的术中成像技术，未来可能会改善肿瘤识别，有可能避免这些患者的过度治疗和治疗不足。这篇叙述性综述概述了结直肠原发PC患者中MFGS发展的时间顺序。
