Bukhari Syed Sarmad, Manan Haris, Khan Mah Muneer, Raza Syed Shahmeer
Department of Neurosurgery, Aga Khan University Hospital, Karachi, Pakistan.
Department of Surgery, Khyber Teaching Hospital, Peshawar, Pakistan.
J Ayub Med Coll Abbottabad. 2018 Apr-Jun;30(2):298-300.
Less than 100 cases of gestational gigantomastia have been described in literature. The aetiology and risk factors are not well-established. Various treatments have been used with some consensus. We present the case of a 47-year-old female who presented to us with bilateral gigantomastia in her 16th week of gestation. She had massively enlarged breasts which were very painful. Relevant laboratory investigations were normal. An incisional biopsy done prior to, and two trucut samples at presentation to us, showed normal breast tissue proliferation. In the absence of adequate pain control, it was decided to electively terminate the pregnancy and give a trial of tamoxifen. She made a rapid recovery following termination without requiring the use of tamoxifen.
文献中报道的妊娠期巨乳症病例不足100例。其病因和危险因素尚未完全明确。目前已达成一些共识,采用了多种治疗方法。我们报告一例47岁女性病例,该患者在妊娠第16周时出现双侧巨乳症。她的乳房极度增大且疼痛剧烈。相关实验室检查结果正常。在来我院就诊前进行的切开活检以及就诊时的两次粗针穿刺活检结果均显示乳腺组织增生正常。由于疼痛无法得到有效控制,决定选择性终止妊娠并试用他莫昔芬。终止妊娠后,她恢复迅速,未使用他莫昔芬。