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兰布尔赘生物

Lambl Excrescences

作者信息

Kondamareddy Divya, Masood Wajeed

机构信息

Atrium Health System

Methodist University, Campbell University School of Osteopathic Medicine.

PMID:29939563
Abstract

Lambl excrescences, a histological term describing rare cardiac growths that develop at the valvular coaptation sites of the heart which are seen as a thin, hypermobile, and filiform strand on an echocardiogram. These filiform strands can be noted on an echocardiogram either incidentally or in association with serious complications such as embolic stroke or acute coronary syndromes after they break off and embolize to distant organs. Lambl excrescences are named after a Bohemian physician-scientist, Vilem Dusan Lambl (1824–1895) who first described these filiform growths on the aortic valve in 1856 in a paper titled, (Weiner medicinische Wochenschrift). Approximately a century later, F. Margarey further described and differentiated these structures histopathologically. Of note, Vilem Dusan Lambl also takes credit for the first original description of the parasite which is named after him,  He scientifically described this parasite in microscopic drawings. He is also credited for giving an initial description of the morphology of bladder cancer cells and spondylosis.

摘要

兰布尔赘生物,这是一个组织学术语,描述罕见的心脏生长物,其在心脏瓣膜贴合部位形成,在超声心动图上表现为细的、活动度高的丝状条索。这些丝状条索在超声心动图上可能偶然被发现,或者在它们断裂并栓塞到远处器官后,与严重并发症如栓塞性中风或急性冠状动脉综合征相关联时被发现。兰布尔赘生物以一位波希米亚医生兼科学家维利姆·杜尚·兰布尔(1824 - 1895)命名,他于1856年在一篇题为《维也纳医学周刊》的论文中首次描述了主动脉瓣上的这些丝状生长物。大约一个世纪后,F. 马加雷对这些结构进行了进一步的组织病理学描述和区分。值得注意的是,维利姆·杜尚·兰布尔还因首次对以他命名的寄生虫进行原始描述而受到赞誉,他在显微镜绘图中对这种寄生虫进行了科学描述。他还因首次描述膀胱癌细胞和脊椎关节强硬的形态而受到赞誉。