Department of Epidemiology, Biostatistics and Occupational Health, McGill University, Montreal, Canada.
McGill International TB Centre, McGill University, Montreal, Canada.
PLoS One. 2018 Jun 25;13(6):e0199706. doi: 10.1371/journal.pone.0199706. eCollection 2018.
Tuberculosis (TB) research is a key component of the End TB Strategy. To track research output, we conducted a bibliometric analysis of TB research from the past decade.
The Web of Science database was searched for publications from January 2007 to December 2016 with "tuberculosis" in the title. References were analysed using the R bibliometrix package. A year-stratified 5% random subset was drawn to extract funding sources and identify research areas.
The annual growth rate of publications was 7.3%, and was highest (13.1%) among Brazil, Russia, India, China and South Africa (BRICS). The USA was the most productive country, with 18.4% of references, followed by India (9.7%), China (7.3%), England (6.5%), and South Africa (3.9%). In the subset analysis, the most common research area was 'fundamental research' (33.8%). Frequently acknowledged funders were US and EU-based, with China and India emerging as top funders. Collaborations appeared more frequently between high-income countries and low/medium income countries (LMICs), with fewer collaborations among LMICs.
The past decade has seen a continued increase in TB publications. While USA continues to dominate research output and funding, BRICS countries have emerged as major research producers and funders. Collaborations among BRICS would enhance future TB research productivity.
结核病（TB）研究是终结结核病策略的关键组成部分。为了跟踪研究成果，我们对过去十年的结核病研究进行了文献计量分析。
在标题中搜索了来自 2007 年 1 月至 2016 年 12 月的结核病研究出版物，使用 Web of Science 数据库。使用 R bibliometrix 包分析参考文献。抽取了每年分层的 5%随机子样本，以提取资金来源和确定研究领域。
出版物的年增长率为 7.3%，巴西、俄罗斯、印度、中国和南非（金砖国家）的增长率最高（13.1%）。美国是最具生产力的国家，占参考文献的 18.4%，其次是印度（9.7%）、中国（7.3%）、英国（6.5%）和南非（3.9%）。在子样本分析中，最常见的研究领域是“基础研究”（33.8%）。经常被认可的资助者是美国和欧盟的，中国和印度成为顶级资助者。高收入国家和低收入/中等收入国家（LMICs）之间的合作更为频繁，而 LMICs 之间的合作较少。
过去十年，结核病出版物持续增加。虽然美国继续主导研究成果和资金，但金砖国家已成为主要的研究生产国和资助国。金砖国家之间的合作将提高未来结核病研究的生产力。
