Maulana Sidik, Lutfian Lutfian, Wardika Izdihar Javier, Fadhli Rahmat, Anggreani Desfara, Haposan Jonathan Hasian, Wildana Fahmi, Efendi Melani Adelia, Platini Hesti, Haroen Hartiah
Doctoral Study Program of Nursing, Faculty of Nursing, Universitas Padjadjaran, Sumedang, 45363, Indonesia.
School of Nursing and Midwifery, Faculty of Medicine, Nursing, and Health Sciences, Monash University, Melbourne, Victoria, 3168, Australia.
Patient Prefer Adherence. 2025 Jul 28;19:2213-2226. doi: 10.2147/PPA.S520341. eCollection 2025.
Current knowledge regarding tuberculosis (TB) medication adherence largely stems from scientific publications. However, to date, the volume and characteristics of studies specifically focused on TB medication adherence in Southeast Asia have not yet been systematically assessed. This study aims to conduct a comprehensive bibliometric analysis of research on medication adherence in TB treatment within this region.
A bibliometric analysis was conducted using the Scopus database to identify research articles related to medication adherence in TB treatment in Southeast Asia, published in English between 2015 and 2024. The analysis included the number of publication trends, country of origin, citation metrics, co-authorship networks, keyword co-occurrence, and the most frequently cited documents.
A total of 146 journal articles were retrieved. Indonesia emerged as the most prolific contributor and demonstrated strong international collaboration. Keyword co-occurrence analysis revealed four major research themes: (1) clinical and demographic characteristics, (2) pharmacological management and disease burden, (3) socio-behavioral factors related to adherence, and (4) digital health-based treatment evaluation. Burst analysis of reference and keyword highlighted emerging research trends, particularly in "primary-community based care" and "digital health interventions", indicating potential trajectories for future research in TB medication adherence.
This study provided an overview of the evolving research landscape on TB medication adherence in Southeast Asia. These findings highlight the growing emphasis on primary-community based care and digital health interventions, pointing toward shaping future research and practice.
目前关于结核病药物依从性的知识主要来源于科学出版物。然而，迄今为止，专门针对东南亚地区结核病药物依从性的研究数量和特点尚未得到系统评估。本研究旨在对该地区结核病治疗中药物依从性的研究进行全面的文献计量分析。
使用Scopus数据库进行文献计量分析，以识别2015年至2024年间以英文发表的与东南亚地区结核病治疗中药物依从性相关的研究文章。分析内容包括发表趋势数量、原产国、引用指标、共同作者网络、关键词共现以及被引用最多的文献。
共检索到146篇期刊文章。印度尼西亚是贡献最多的国家，并展现出强大的国际合作。关键词共现分析揭示了四个主要研究主题：（1）临床和人口统计学特征；（2）药物管理和疾病负担；（3）与依从性相关的社会行为因素；（4）基于数字健康的治疗评估。参考文献和关键词的突发分析突出了新兴研究趋势，特别是在“基于初级社区的护理”和“数字健康干预”方面，表明了结核病药物依从性未来研究的潜在轨迹。
本研究概述了东南亚地区结核病药物依从性研究的发展态势。这些发现凸显了对基于初级社区的护理和数字健康干预的日益重视，为未来的研究和实践指明了方向。
