无皮肤表现的胰高血糖素瘤
Glucagonoma without cutaneous manifestations.
作者信息
Parr J H, Ramsay I D, Keeling P W, Thompson R P, Mallinson C N
出版信息
Postgrad Med J. 1985 Aug;61(718):737-8. doi: 10.1136/pgmj.61.718.737.
A 63 year old man presented with features of the glucagonoma syndrome, that is thromboembolic disease, weight loss, raised sedimentation rate, diabetes mellitus, hypoproteinaemia and reduced plasma amino acid levels, but without necrolytic migratory erythema. The plasma glucagon level was raised and the tumour was demonstrated by abdominal CT scan. Immunofluorescent studies of the resected tumour confirmed the diagnosis. The normal tissue zinc status supports the view that necrolytic migratory erythema is related to zinc deficiency.
一名63岁男性出现了胰高血糖素瘤综合征的症状，即血栓栓塞性疾病、体重减轻、血沉加快、糖尿病、低蛋白血症和血浆氨基酸水平降低，但无坏死松解性游走性红斑。血浆胰高血糖素水平升高，腹部CT扫描显示有肿瘤。对切除肿瘤的免疫荧光研究证实了诊断。正常组织的锌状态支持坏死松解性游走性红斑与锌缺乏有关这一观点。
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