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[血友病患者中抗LAV抗体的患病率及其与免疫状态的相关性]

[Prevalence of anti-LAV antibodies in hemophiliacs, correlation with the immunological state].

作者信息

Aymard J P, Janot C, Chermann J C, Briquel M E, Perrier P, Alexandre P, Streiff F

出版信息

Rev Fr Transfus Immunohematol. 1985 Jun;28(3):261-5. doi: 10.1016/s0338-4535(85)80117-3.

DOI:10.1016/s0338-4535(85)80117-3
PMID:2994201
Abstract

49 french haemophiliacs (haemophilia A: 41 patients; haemophilia B: 8 patients) were serologicaly tested for LAV antibodies: 10 patients (20.4%) were seropositive including 9 (21.9%) with haemophilia A and 1 (12,5%) with haemophilia B. Between seronegative and seropositive patients total lymphocyte and T-lymphocyte sub-populations counts were not significantly different. The mean serum IgG level was higher and palpable lymphadenopathy more frequently encountered among seropositive patients.

摘要

对49名法国血友病患者(甲型血友病:41例;乙型血友病:8例)进行了淋巴细胞脉络丛脑膜炎病毒(LAV)抗体的血清学检测:10例患者(20.4%)血清呈阳性,其中9例(21.9%)为甲型血友病患者,1例(12.5%)为乙型血友病患者。血清阴性和血清阳性患者之间的总淋巴细胞和T淋巴细胞亚群计数无显著差异。血清阳性患者的平均血清IgG水平较高,且更常出现可触及的淋巴结病。

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