Wakasa K, Sakurai M, Okamura J, Kuroda C
Virchows Arch A Pathol Anat Histopathol. 1985;407(3):259-70. doi: 10.1007/BF00710651.
We studied the pathological findings in 28 small hepatocellular carcinomas (less than 5 cm in diameter), especially the mode of invasion. Seventeen of the 28 lesions were encapsulated. Capsular invasion was present in 14 of the 17 encapsulated tumours. Vascular invasion was found in 12 of the 28 tumours. The small hepatocellular carcinoma, even when encapsulated, frequently invaded blood vessels and adjacent liver tissue, in spite of frequent vascular invasion, distant metastasis was seen in only 1 of the 28 tumours.
我们研究了28例小肝细胞癌（直径小于5厘米）的病理结果，尤其是浸润方式。28个病灶中有17个有包膜。17个有包膜的肿瘤中有14个存在包膜侵犯。28个肿瘤中有12个发现血管侵犯。小肝细胞癌即使有包膜，也经常侵犯血管和邻近肝组织，尽管血管侵犯常见，但28个肿瘤中仅1个出现远处转移。
