Wang Jing-Si, Zhang Qiu-Yun, Cheng Jin-Lian, Chen Lan-Yu, Yao Nai-Li, Sun Gui-Zhi, Chu Yu-Ling
Department of Hepatology, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing, 100010, China.
College of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing, 100069, China.
Chin J Integr Med. 2018 Sep;24(9):713-720. doi: 10.1007/s11655-018-3007-1. Epub 2018 Jun 25.
Hepatic fibrosis is a common feature of almost all chronic liver diseases. Formation of new vessels (angiogenesis) is a process strictly related to the progressive fibrogenesis which leads to cirrhosis and liver cancer. This review mainly concerns the relationship between angiogenesis and hepatic fibrosis, by considering the mechanism of angiogenesis, cells in angiogenesis, anti-angiogenic and Chinese medicine therapies.
肝纤维化是几乎所有慢性肝病的共同特征。新血管形成(血管生成)是一个与导致肝硬化和肝癌的进行性纤维化密切相关的过程。本综述主要通过考虑血管生成的机制、血管生成中的细胞、抗血管生成疗法和中医药疗法,探讨血管生成与肝纤维化之间的关系。