病例报告：暴发性鼠型斑疹伤寒伴癫痫持续状态和多器官衰竭：尸检病例及鼠型斑疹伤寒的神经表现综述。
Case Report: Fulminant Murine Typhus Presenting with Status Epilepticus and Multi-Organ Failure: an Autopsy Case and a Review of the Neurologic Presentations of Murine Typhus.
机构信息
Department of Medicine, Long School of Medicine at University of Texas Health, San Antonio, Texas.
Division of Pulmonary and Critical Care Medicine, Department of Medicine, Long School of Medicine at University of Texas Health, San Antonio, Texas.
出版信息
Am J Trop Med Hyg. 2018 Aug;99(2):306-309. doi: 10.4269/ajtmh.18-0084. Epub 2018 Jun 21.
Abstract
Murine typhus (MT) is an important cause of febrile illness in endemic areas, and there is an epidemiologic resurgence of this infection currently transpiring in Texas and California. Fatal cases and severe neurological complications are rare. A fatal case of MT in a middle-aged man is reported with a course culminating in multi-organ failure and refractory status epilepticus. An autopsy revealed hemorrhagic pneumonia, acute tubular necrosis, and ischemic necrosis in the liver, adrenals, and brain. We have also reviewed the neurologic complications of MT.
摘要
鼠型斑疹伤寒（MT）是地方性流行地区发热性疾病的重要病因，目前德克萨斯州和加利福尼亚州正出现这种感染的流行回升。致命病例和严重神经系统并发症较为少见。本文报告了一例中年男性 MT 致死病例，其病程最终导致多器官衰竭和难治性癫痫持续状态。尸检显示存在出血性肺炎、急性肾小管坏死和肝、肾上腺和脑的缺血性坏死。我们还回顾了 MT 的神经系统并发症。
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2
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Infez Med. 2017 Jun 1;25(2):91-97.
3
Fatal Flea-Borne Typhus in Texas: A Retrospective Case Series, 1985-2015.
Am J Trop Med Hyg. 2017 May;96(5):1088-1093. doi: 10.4269/ajtmh.16-0465.
4
Typhus Group Rickettsiosis, Texas, USA, 2003-2013.
Emerg Infect Dis. 2017 Apr;23(4):645-648. doi: 10.3201/eid2304.160958.
5
Clinical and laboratory characteristics, epidemiology, and outcomes of murine typhus: A systematic review.
Acta Trop. 2017 Feb;166:16-24. doi: 10.1016/j.actatropica.2016.10.018. Epub 2016 Oct 29.
6
Misdiagnosed murine typhus in a patient with multiple cerebral infarctions and hemorrhage: a case report.
BMC Neurol. 2015 Jul 30;15:121. doi: 10.1186/s12883-015-0383-4.
7
Risk factors for fatal outcome from rocky mountain spotted Fever in a highly endemic area-Arizona, 2002-2011.
Clin Infect Dis. 2015 Jun 1;60(11):1659-66. doi: 10.1093/cid/civ116. Epub 2015 Feb 19.
8
Epidemiological, clinical and laboratory features of murine typhus in central Tunisia.
Med Mal Infect. 2015 Apr;45(4):124-7. doi: 10.1016/j.medmal.2015.01.009. Epub 2015 Feb 14.
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Scrub typhus: audit of an outbreak.
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