马来西亚半岛通过血清学诊断鼠型斑疹伤寒：立克次体病、钩端螺旋体病和登革热共同流行的病例报告
Diagnosis of Murine Typhus by Serology in Peninsular Malaysia: A Case Report Where Rickettsial Illnesses, Leptospirosis and Dengue Co-Circulate.
作者信息
Yuhana Yazli, Tanganuchitcharnchai Ampai, Sujariyakul Pimpan, Sonthayanon Piengchan, Chotivanich Kesinee, Paris Daniel H, Pukrittayakamee Sasithon, Blacksell Stuart D, Hanboonkunupakarn Borimas
机构信息
Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand.
Infectious Diseases Unit, Department of Internal Medicine, Universiti Teknologi MARA, Sungai Buloh 47000, Malaysia.
出版信息
Trop Med Infect Dis. 2019 Jan 31;4(1):23. doi: 10.3390/tropicalmed4010023.
Murine typhus is a rarely diagnosed cause of acute febrile illness in Malaysia, and its true disease burden is unknown. We report a case of an acute murine typhus infection in a patient living in a small city in Peninsular Malaysia, presenting with fever, rash, and headache. Unresponsive to the initial empirical treatment for leptospirosis, he showed a rapid response to doxycycline when murine typhus was diagnosed later. This case highlights the importance of considering murine typhus as a diagnostic in cases of acute febrile illness in urban and sub-urban areas, such as that of in Peninsular Malaysia.
鼠型斑疹伤寒在马来西亚是急性发热性疾病的一种罕见诊断病因，其真实的疾病负担尚不清楚。我们报告了一例居住在马来西亚半岛一个小城市的患者感染急性鼠型斑疹伤寒的病例，该患者表现为发热、皮疹和头痛。最初对钩端螺旋体病的经验性治疗无效，在后来诊断为鼠型斑疹伤寒时，他对多西环素迅速产生反应。该病例凸显了在城市和郊区（如马来西亚半岛）的急性发热性疾病病例中，将鼠型斑疹伤寒作为一种诊断考虑的重要性。
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