Di Muzio M, Gambaro A M L, Colagiovanni V, Valentini L, Di Simone E, Monti M
Clin Exp Obstet Gynecol. 2016;43(6):862-865.
To evaluate pregnancy rate after diagnostic and operative hysteroscopy in nulliparous patients with inter- tility of unknown cause.
The authors conducted this study on 92 nulliparous patients with unexplained infer- tility that underwent diagnostic hysteroscopy which showed an uterine lesion (submucous fibroids, uterine septa, polyps, synechias) and underwent operative hysteroscopy to remove the lesion between 2007 and 2011. Patients' data were retrospectively extrapolated from patient's charts, then the patients were called to ask if they had pregnancies after hysteroscopic surgery.
The present study showed a significant increase in pregnancy rate after hysteroscopic surgery (85% during the two years after the surgery). The most common endocavitary lesions were endometrial polyps (21%), uterine septa (25%), and submucous myomas (18%).
Ac- cording to the present data, hysteroscopic evaluation of nulliparous women with unexplained infertility could be useful to detect lesions not diagnosed with other tests, and the treatment of these endocavitary lesions plays an important role in the diagnostic and therapeutic iter. The results show-a pregnancy rate of 85% in the patients treated for endocavitary lesions, but 15% of the patients, despite a normal uterine cavity, continue to have unexplained infertility and are classified as idiopathic infertility.
评估不明原因不孕的未生育患者在诊断性和手术性宫腔镜检查后的妊娠率。
作者对92例不明原因不孕的未生育患者进行了研究，这些患者在2007年至2011年间接受了诊断性宫腔镜检查，检查显示存在子宫病变（黏膜下肌瘤、子宫纵隔、息肉、粘连），并接受了手术性宫腔镜检查以切除病变。患者数据从病历中回顾性提取，然后致电患者询问宫腔镜手术后是否怀孕。
本研究显示宫腔镜手术后妊娠率显著提高（术后两年内为85%）。最常见的宫腔内病变是子宫内膜息肉（21%）、子宫纵隔（25%）和黏膜下肌瘤（18%）。
根据目前的数据，对不明原因不孕的未生育女性进行宫腔镜评估有助于发现其他检查未诊断出的病变，这些宫腔内病变的治疗在诊断和治疗过程中起着重要作用。结果显示，接受宫腔内病变治疗的患者妊娠率为85%，但15%的患者尽管子宫腔正常，仍持续存在不明原因不孕，被归类为特发性不孕。
