Lapuente-Ocamica O, Ugarte L, Cuadra M, Lopez-Picado A, Maestro L, Lete I
Clin Exp Obstet Gynecol. 2016;43(6):905-910.
Growing teratoma syndrome is an uncommon complication of malignant germ cell cancer, characterised by the development of large tumours during or after chemotherapy, despite normalisation of tumour marker levels and metastasis, which contain only mature teratoma. Given its low incidence, little is data available. The authors present the case of a 15-year-old girl with a growing teratoma and the literature review outlines the current knowledge of its pathogenesis, common sites, diagnosis, natural course, treatment, and prognosis.
生长性畸胎瘤综合征是恶性生殖细胞癌的一种罕见并发症，其特征是在化疗期间或化疗后出现大肿瘤，尽管肿瘤标志物水平正常且无转移，而肿瘤仅包含成熟畸胎瘤。鉴于其发病率低，可用数据很少。作者报告了一名15岁患有生长性畸胎瘤的女孩病例，并通过文献综述概述了其发病机制、常见部位、诊断、自然病程、治疗及预后的现有知识。
