Essien E M, Okogun J I, Adelakun A
Afr J Med Med Sci. 1985 Mar-Jun;14(1-2):83-8.
The coagulant properties of root bark and root wood extracts of Fagara xanthoxyloides lam plant are reported. Results of an earlier report which showed that the aqueous extract of the root shortened both the PT and PTT of normal and FVIIIC-deficient plasma are confirmed as well as the absence of many such effects on FIXC-deficient plasma. Root bark manifested twice as much potency as an equal concentration of root wood. The activity could still be demonstrated in the residue of root bark after the lyophilized aqueous extract had been successively extracted with methanol and hexane. It is suggested that these results may have clinical implications.
报道了花椒属植物黄皮树的根皮和根木提取物的凝血特性。早期一份报告显示，该植物根的水提取物可缩短正常血浆和FVIIIC缺乏血浆的凝血酶原时间（PT）和部分凝血活酶时间（PTT），本研究结果证实了这一点，同时也证实了该提取物对FIXC缺乏血浆没有许多此类影响。在相同浓度下，根皮的效力是根木的两倍。冻干水提取物先后用甲醇和己烷萃取后，根皮残渣仍具有活性。这些结果可能具有临床意义。
