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神经血管护理创新的介绍:患者选择与随机分配

The Introduction of Innovations in Neurovascular Care: Patient Selection and Randomized Allocation.

作者信息

Fahed Robert, Darsaut Tim E, Raymond Jean

机构信息

Department of Interventional Neuroradiology, Rothschild Foundation Hospital, Paris, France; Service of Neuroradiology, Department of Radiology, Centre Hospitalier de l'Université de Montréal, Notre-Dame Hospital, Montreal, Quebec, Canada.

Division of Neurosurgery, Department of Surgery, University of Alberta Hospital, Mackenzie Health Sciences Center, Edmonton, Alberta, Canada.

出版信息

World Neurosurg. 2018 Oct;118:e99-e104. doi: 10.1016/j.wneu.2018.06.127. Epub 2018 Jun 23.

Abstract

Most neurovascular innovations have been introduced by using case series followed by observational studies. A better approach would be a pragmatic randomized trial. Two important aspects of trial design, patient selection and randomized allocation, remain poorly understood. We discuss the role trial methodology can play in the protection of patients being offered innovative treatments.

摘要

大多数神经血管创新技术都是先通过病例系列研究引入,随后进行观察性研究。更好的方法是开展务实的随机试验。试验设计的两个重要方面,即患者选择和随机分配,仍然未得到充分理解。我们讨论了试验方法在保护接受创新治疗的患者方面可以发挥的作用。

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