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胸主动脉腔内修复术后食管坏死:一种微创血管腔内治疗方法——一种严重并发症。

Oesophageal necrosis after thoracic endovascular aortic repair: a minimally invasive endovascular approach-a dramatic complication.

作者信息

Papakonstantinou Nikolaos A, Patris Vasileios, Antonopoulos Constantine N, Samiotis Ilias, Argiriou Mihalis

机构信息

Department of Cardiovascular and Thoracic Surgery, General Hospital of Athens "Evangelismos", Athens, Greece.

出版信息

Interact Cardiovasc Thorac Surg. 2019 Jan 1;28(1):9-16. doi: 10.1093/icvts/ivy193.

Abstract

There are few cases in the literature reporting dysphagia caused by oesophageal compression by the aorta due to acute or chronic aortic pathology. This type of dysphagia is called dysphagia aortica. Thoracic endovascular aortic repair is nowadays the treatment of choice for anatomically suitable patients experiencing complicated Type B aortic dissection. Oesophageal necrosis is a rare but fatal complication following thoracic endovascular aortic repair. Extrinsic oesophageal compression by the thrombosed aneurysmal sac, a mediastinal haematoma or extensive thrombosis in the false lumen of a dissected aorta and acute vascular occlusion of the oesophageal supply are possible mechanisms. When oesophageal necrosis is suspected, endoscopic examination and computed tomography imaging should be performed repeatedly. Oesophagoscopy will confirm the diagnosis revealing a black, diffusely necrotic and ulcerated oesophageal mucosa. It is critical to intervene before full-thickness oesophageal wall necrosis and mediastinitis occur. Guidelines are absent because of the rarity of this complication. Moreover, lack of a large series does not permit the establishment of guidelines either. However, oesophagectomy of the impaired oesophagus is the only chance for survival. Unfortunately, survival rates are disappointing. Prevention and awareness is the cornerstone of success. Early endoscopic examination when oesophageal necrosis is suspected due to even minimal symptoms will detect this fatal menace on time.

摘要

文献中鲜有因急性或慢性主动脉病变导致主动脉压迫食管引起吞咽困难的病例报道。这种类型的吞咽困难被称为主动脉性吞咽困难。对于解剖结构适合的复杂性B型主动脉夹层患者,胸主动脉腔内修复术如今是首选治疗方法。食管坏死是胸主动脉腔内修复术后一种罕见但致命的并发症。血栓形成的动脉瘤囊、纵隔血肿或夹层主动脉假腔内广泛血栓形成对食管的外在压迫以及食管供血的急性血管闭塞都是可能的机制。当怀疑有食管坏死时,应反复进行内镜检查和计算机断层扫描成像。食管镜检查将通过显示黑色、弥漫性坏死和溃疡的食管黏膜来确诊。在食管壁全层坏死和纵隔炎发生之前进行干预至关重要。由于这种并发症罕见,所以缺乏相关指南。此外,缺乏大量病例系列也无法制定指南。然而,切除受损食管是唯一的生存机会。不幸的是,生存率令人失望。预防和提高认识是成功的基石。当因哪怕最轻微的症状怀疑有食管坏死时尽早进行内镜检查将及时发现这种致命威胁。

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