Qin Shuang-Shuang, Zhu Yan-Xia, Wei Kun-Hua, Li Ming-Jie, Miao Jian-Hua, Zhang Zhong-Yi
College of Crop Sciences, Fujian Agricultural and Forestry University, Fuzhou 350002, China.
Guangxi Key Laboratory of Medicinal Resources Protection and Genetic Improvement, Guangxi Botanical Garden of Medicinal Plant, Nanning 530023, China.
Zhongguo Zhong Yao Za Zhi. 2018 Jun;43(11):2216-2223. doi: 10.19540/j.cnki.cjcmm.20180227.001.
Spatholobi Caulis, the vine stem of Spatholobus suberectus and widely used in China and Southeast Asian nations, has the effects on nourishing the blood and promoting blood flow, regulating menstruation and relieving pain, and invigorating the nerves. Through consulting the herbal textual and local chronicles, we summarized the original textual research and medicinal evolution on Spatholobi Caulis to analyze the changes of varieties in different historical periods. Further, the major active ingredient in Spatholobi Caulis was discussed. According to the literature to date, 60 flavonoids compounds have been isolated and could be divided into isoflavones, dihydroflavones, flavanols, dihydroflavonols, procyaninides, chalcones, pterocarpans, isoflavanols, isoflavanones and aurone according to their molecular structures. These indicative ingredients in Spatholobi Caulis showed pharmacological activities on regulation of the blood system, anti-tumor, anti-oxidation, anti-virus, anti-bacteria and inhibition of melanin deposition. This review will provide reference and basis for the sustainable use of resources and industry development on Spatholobi Caulis.
鸡血藤为密花豆的藤茎，在中国及东南亚国家广泛应用，具有补血活血、调经止痛、舒筋活络之功效。通过查阅本草文献及地方史志，总结鸡血藤的本草考证及药用沿革，分析不同历史时期品种变迁情况。此外，对鸡血藤主要活性成分进行探讨。据现有文献，已从鸡血藤中分离出60个黄酮类化合物，根据其分子结构可分为异黄酮、二氢黄酮、黄烷醇、二氢黄酮醇、原花青素、查耳酮、紫檀素、异黄烷醇、异黄烷酮及噢哢。鸡血藤中这些标志性成分具有调节血液系统、抗肿瘤、抗氧化、抗病毒、抗菌及抑制黑色素沉着等药理活性。本综述可为鸡血藤资源的可持续利用及产业发展提供参考和依据。
