从……中分离出的芳基四氢萘型木脂素。 （原英文文本不完整，此译文根据补充完整后的常见理解给出）
Aryl-tetralin-type lignan isolated from .
作者信息
Wang Li-Na, Qin Ling-Ling, He Jun-Lin, Li Xiao-Hua, Cao Zhi-Xing, Gu Yu-Cheng, Deng Fang, Deng Yun
机构信息
The Ministry of Education Key Laboratory of Standardization of Chinese Herbal Medicine, State Key Laboratory, Breeding Base of Systematic Research Development and Utilization of Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine , Chengdu 611137 , China.
Syngenta Jealott's Hill International Research Centre , Berkshire RG42 6EY , UK.
出版信息
J Asian Nat Prod Res. 2019 Oct;21(10):999-1004. doi: 10.1080/10286020.2018.1487957. Epub 2018 Jun 26.
Three aryl-tetralin-type lignans, including 2 previously undescribed compounds, were isolated from the root of . The structures of the new compounds were elucidated by 1D- and 2D-NMR spectroscopic analyses and mass spectrometry. Experimental and calculated ECD were used to determine the absolute configurations. The isolated compounds were evaluated for cytotoxicity against two cell lines (MV4-11 and MDA-MB-231) and compound exhibited moderate growth inhibition against MDA-MB-231 cell line with IC value of 15.76 μM.
从……的根中分离出三种芳基四氢萘型木脂素，其中包括2种此前未被描述的化合物。通过一维和二维核磁共振光谱分析以及质谱对新化合物的结构进行了阐明。利用实验和计算的电子圆二色谱来确定绝对构型。对分离得到的化合物针对两种细胞系（MV4-11和MDA-MB-231）进行了细胞毒性评估，化合物……对MDA-MB-231细胞系表现出中等程度的生长抑制作用，IC值为15.76 μM。
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