地榆中新木脂素的两种新鼠李吡喃糖苷。

Two new rhamnopyranosides of neolignans from Sanguisorba officinalis.

作者信息

Hu Jiang, Shi Xiao-Dong, Chen Jian-Gang, Li Chang-Sheng

机构信息

College of Biological Resources and Environment Science, Qujing Normal University, Qujing, China.

出版信息

J Asian Nat Prod Res. 2012;14(2):171-5. doi: 10.1080/10286020.2011.634803.

DOI:10.1080/10286020.2011.634803

PMID:22296158

Abstract

Two new rhamnopyranosides of neolignans, (7S,8R)-4,9,5',9'-tetrahydroxy-3,3'-dimethoxy-8-O-4'-neolignan-7-O-α-l-rhamnopyranoside (1) and (7S,8R)-4,9,9'-trihydroxy-3,3',5'-trimethoxy-8-O-4'-neolignan-7-O-α-l-rhamnopyranoside (2), together with a known compound (7S,8R)-4,7,9,9'-tetrahydroxy-3,3'-dimethoxy-8-O-4'-neolignan (3), were isolated from the 80% EtOH extract of the roots of Sanguisorba officinalis. Their structures were characterized by spectroscopic analysis including 1D NMR, 2D NMR, and HR-ESI-MS, and chemical method.

摘要

从地榆根的80%乙醇提取物中分离出两种新的新木脂素鼠李吡喃糖苷，即(7S,8R)-4,9,5',9'-四羟基-3,3'-二甲氧基-8-O-4'-新木脂素-7-O-α-L-鼠李吡喃糖苷（1）和(7S,8R)-4,9,9'-三羟基-3,3',5'-三甲氧基-8-O-4'-新木脂素-7-O-α-L-鼠李吡喃糖苷（2），以及一种已知化合物(7S,8R)-4,7,9,9'-四羟基-3,3'-二甲氧基-8-O-4'-新木脂素（3）。通过包括一维核磁共振、二维核磁共振和高分辨电喷雾电离质谱在内的光谱分析以及化学方法对它们的结构进行了表征。