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登革热相关的可逆性胼胝体病变综合征:一例报告

Reversible splenial lesion syndrome associated with dengue fever: a case report.

作者信息

Sathananthasarma Pavithra, Weeratunga Praveen Nilendra, Chang Thashi

机构信息

Professorial Medical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka.

Department of Clinical Medicine, University of Colombo, Colombo, Sri Lanka.

出版信息

BMC Res Notes. 2018 Jun 27;11(1):412. doi: 10.1186/s13104-018-3491-6.

DOI:10.1186/s13104-018-3491-6
PMID:29945676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6020389/
Abstract

BACKGROUND

Dengue virus infection in humans can lead to a wide range of clinical manifestations, from mild fever to potentially fatal dengue shock syndrome. The incidence of dengue fever is on the rise in tropical countries. Due to the increasing incidence of dengue fever worldwide, atypical manifestations of the disease are increasingly reported. In this article we report a patient with dengue haemorrhagic fever who presented with reversible splenial lesion syndrome.

CASE PRESENTATION

A 24-year-old Sri Lankan man who presented with fever and confusion was eventually diagnosed to have reversible splenial lesion syndrome based on brain imaging. Clinical, serological and haematological parameters confirmed a diagnosis of dengue haemorrhagic fever. His presentation, assessment, and management are described in this case report.

CONCLUSION

Reversible splenial lesion syndrome is a condition which is radiologically characterized by reversible lesion in the splenium of the corpus callosum. It is associated with infectious and non-infectious aetiologies. This case report highlights the occurrence of reversible splenial lesion syndrome as a presenting feature of the expanding list of unusual neurological manifestations of dengue infection.

摘要

背景

人类感染登革病毒可导致广泛的临床表现,从轻度发热到可能致命的登革热休克综合征。热带国家登革热的发病率正在上升。由于全球登革热发病率不断增加,该疾病的非典型表现报告也越来越多。在本文中,我们报告了一名患有登革出血热并出现可逆性胼胝体压部病变综合征的患者。

病例介绍

一名24岁的斯里兰卡男子,出现发热和意识模糊症状,最终根据脑部影像学检查被诊断为可逆性胼胝体压部病变综合征。临床、血清学和血液学参数证实诊断为登革出血热。本病例报告描述了他的临床表现、评估和治疗情况。

结论

可逆性胼胝体压部病变综合征是一种在影像学上以胼胝体压部可逆性病变为特征的疾病。它与感染性和非感染性病因有关。本病例报告强调了可逆性胼胝体压部病变综合征作为登革热感染不寻常神经表现不断增加的一个特征的出现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0de4/6020389/066622e5acca/13104_2018_3491_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0de4/6020389/c75753a1d810/13104_2018_3491_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0de4/6020389/066622e5acca/13104_2018_3491_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0de4/6020389/c75753a1d810/13104_2018_3491_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0de4/6020389/066622e5acca/13104_2018_3491_Fig2_HTML.jpg

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