Yuan Ligong, Mao Yousheng
Department of Thoracic Surgery, National Cancer Center, Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.
Zhongguo Fei Ai Za Zhi. 2018 Jun 20;21(6):493-497. doi: 10.3779/j.issn.1009-3419.2018.06.10.
Superior sulcus tumor of the lung is a bronchogenic tumor occurred in the apex of the upper lobe of the lung and is a unique clinical subtype of non-small cell lung cancer (NSCLC), which account for less than 5% of all bronchogenic carcinomas. It often involves the first rib, brachial plexus, subclavian vessels, sympathetic chain, stellate ganglion or vertebra. A lot of progress has been achieved in the treatment of superior sulcus tumor over the past decades. Several clinical trials reported in recent years have confirmed that concurrent chemoradiotherapy followed by surgical resection can improve the rate of complete resection, local control and pathological remission of the tumor, and prolong the total-survival time. It has become the most effective treatment mode for the superior sulcus tumor, and recommended as a standard treatment mode for superior sulcus tumor by National Comprehensive Cancer Network (NCCN) and American College of Chest Physicians (ACCP) guidelines. This article reviews relevant literatures at home and abroad, and briefly introduces the advances in surgical treatment and comprehensive treatment of superior sulcus tumor. .
肺上沟瘤是发生于肺上叶尖部的一种支气管源性肿瘤,是非小细胞肺癌(NSCLC)的一种独特临床亚型,占所有支气管源性癌的比例不到5%。它常累及第一肋骨、臂丛神经、锁骨下血管、交感神经链、星状神经节或椎体。在过去几十年中,肺上沟瘤的治疗取得了很大进展。近年来报道的几项临床试验证实,同步放化疗后行手术切除可提高肿瘤的完全切除率、局部控制率和病理缓解率,并延长总生存时间。它已成为肺上沟瘤最有效的治疗模式,并被美国国立综合癌症网络(NCCN)和美国胸科医师学会(ACCP)指南推荐为肺上沟瘤的标准治疗模式。本文回顾了国内外相关文献,并简要介绍了肺上沟瘤手术治疗和综合治疗的进展。