School of Environment and Natural Resources, Doon University, Dehradun, Uttarakhand, 248001, India.
Environ Sci Pollut Res Int. 2018 Sep;25(25):25336-25347. doi: 10.1007/s11356-018-2581-2. Epub 2018 Jun 26.
Consumption of high NO containing water may pose serious health hazard especially in children (< 5 years). The source of NO in groundwater includes surface leaching from wastewater and waste dump sites, animal excreta disposal, industrial effluents, and N-based fertilizers, etc. This study aimed to investigate the concentration of NO in groundwater of 14 intensively cultivated districts of Malwa Punjab, India, and its possible health hazards in local residents. The sampling of 76 sites revealed the concentration of NO in ranges of 38.45-198.05 mgL, and over 92% sites showed the high level of it than the safe limits as decided by the Bureau of Indian standards (45 mg L) and World Health Organization (50 mg L). The possible health hazards of high NO intake was estimated using USEPA human health risk assessment (HHRA) model for both adult and children. Results of this study suggested the chronic daily intake (CDI) in the ranges of 1.09-5.65 and 2.56-13.20 in adult and children population of this region, respectively. The hazard quotient (HQ) value was > 1 in most sampling locations ranging 1.09-5.65 for the adult and 2.56-13.20 for children population of Malwa. This study indicates that 93.42% adult and 100% young population of the Malwa are at higher risk of chronic toxicity by excess NO intake. The HHRA results suggested a high vulnerability of a local community to NO toxicity in this region; therefore, there is an instant need to take preventive measures to safeguard the health of local residents.
饮用水中摄入高浓度的硝酸盐可能会对健康造成严重危害,尤其是对儿童(<5 岁)。地下水中的硝酸盐来源包括来自废水和废物倾倒场的地表淋滤、动物粪便处理、工业废水和含氮肥料等。本研究旨在调查印度马尔瓦邦 14 个集约化种植区地下水硝酸盐的浓度及其对当地居民可能产生的健康危害。对 76 个地点的采样显示,硝酸盐的浓度范围在 38.45-198.05mg/L 之间,超过 92%的地点的硝酸盐浓度高于印度标准局(45mg/L)和世界卫生组织(50mg/L)规定的安全限值。本研究使用美国环保署人类健康风险评估(HHRA)模型对成人和儿童进行了高硝酸盐摄入的潜在健康危害评估。结果表明,该地区成人和儿童的慢性日摄入量(CDI)分别在 1.09-5.65 和 2.56-13.20 范围内。在大多数采样点,危害系数(HQ)值>1,成人范围为 1.09-5.65,儿童范围为 2.56-13.20。本研究表明,马尔瓦地区 93.42%的成年人口和 100%的年轻人口由于过量摄入硝酸盐而面临更高的慢性毒性风险。HHRA 结果表明,该地区的当地社区对硝酸盐毒性的脆弱性很高;因此,需要立即采取预防措施,保护当地居民的健康。