Penuelas Josep, Sardans Jordi
CSIC, Global Ecology Unit CREAF-CSIC-UAB, 08193 Bellaterra, Barcelona, Catalonia, Spain.
CREAF, 08193 Cerdanyola del Vallès, Barcelona, Catalonia, Spain.
Eco Environ Health. 2023 Aug 24;2(4):246-251. doi: 10.1016/j.eehl.2023.08.003. eCollection 2023 Dec.
Human-induced inputs of nitrogen (N) and phosphorus (P) into the biosphere have reached unprecedented levels, particularly N, leading to an escalating global anthropogenic N:P ratio. This ratio has emerged as a significant driver of environmental change, impacting organisms, ecosystems, and global food security. However, the implications of this ratio for human health have been largely overlooked and remain uncertain. This article aims to fill this knowledge gap by exploring the potential effects of N:P ratios on both non-infectious and infectious diseases. Preliminary data emphasize the importance of investigating the influence of N:P ratios on human health, suggesting a potential role in the rise of non-infectious diseases, such as cancer, as well as the proliferation of infectious diseases, including Zika and malaria. These findings highlight the urgent need for increased attention from the scientific community and policymakers regarding the complex impacts of the human-induced biospheric N:P ratio. It is crucial to investigate and understand the underlying mechanisms and drivers behind these effects. Furthermore, there is significant potential for improving human health through the manipulation of N:P ratios and the availability of N and P. This applies not only to medical treatments but also to innovative fertilizer management strategies. These avenues present promising opportunities to address the challenges associated with human health in an ever-changing world.
人类向生物圈输入的氮（N）和磷（P）已达到前所未有的水平，尤其是氮，导致全球人为氮磷比不断攀升。这一比例已成为环境变化的重要驱动因素，影响着生物、生态系统和全球粮食安全。然而，这一比例对人类健康的影响在很大程度上被忽视了，仍不确定。本文旨在通过探讨氮磷比对非传染性疾病和传染性疾病的潜在影响来填补这一知识空白。初步数据强调了研究氮磷比对人类健康影响的重要性，表明其在癌症等非传染性疾病增加以及寨卡病毒和疟疾等传染病扩散中可能发挥的作用。这些发现凸显了科学界和政策制定者迫切需要更多关注人为引起的生物圈氮磷比的复杂影响。研究和了解这些影响背后的潜在机制和驱动因素至关重要。此外，通过控制氮磷比以及氮和磷的可利用性来改善人类健康具有巨大潜力。这不仅适用于医学治疗，也适用于创新的肥料管理策略。这些途径为应对不断变化世界中与人类健康相关的挑战提供了充满希望的机会。
