Reproductive Medicine Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Department of Gynecology and Obstetrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.
Front Med. 2019 Feb;13(1):121-125. doi: 10.1007/s11684-018-0615-2. Epub 2018 Jun 27.
This retrospective study aims to demonstrate the effect of antitubercular treatment (ATT) on the pregnancy outcomes and prognoses of patients with genital tuberculosis (GTB) who had received laparoscopy and/or hysteroscopy. This study included 78 patients with infertility and who were diagnosed with GTB through laparoscopy and/or hysteroscopy over the period of November 2005 to October 2015. The recruited patients were divided into ATT and nonATT groups on the basis of ATT duration. The GTB recurrence rates, menstrual patterns, and pregnancy outcomes of the patients were determined at follow-up. Among the 78 patients, 46 received ATT and 32 did not receive ATT. The menstrual volumes of patients in the ATT group significantly decreased relative to those of patients in the nonATT group. GTB did not recur among all patients regardless of treatment. A total of 11 pregnancies (36.7%) in the ATT group and 19 pregnancies (63.3%) in the nonATT group were observed. Pregnancy rates significantly differed (P = 0.002) between the two groups. ATT may decrease the menstrual volume and pregnancy rates of patients who were diagnosed with GTB through laparoscopy and/or hysteroscopy. In addition, ATT did not improve the prognosis of patients with chronic GTB.
本回顾性研究旨在展示抗结核治疗（ATT）对接受腹腔镜和/或宫腔镜检查诊断为生殖器结核（GTB）的患者的妊娠结局和预后的影响。该研究纳入了 2005 年 11 月至 2015 年 10 月期间因不孕症接受腹腔镜和/或宫腔镜检查诊断为 GTB 的 78 例患者。根据 ATT 持续时间，将纳入的患者分为 ATT 和非 ATT 组。在随访时确定患者的 GTB 复发率、月经模式和妊娠结局。78 例患者中，46 例接受 ATT，32 例未接受 ATT。ATT 组患者的月经量明显少于非 ATT 组。无论是否接受治疗，所有患者均未出现 GTB 复发。ATT 组中有 11 例妊娠（36.7%），非 ATT 组中有 19 例妊娠（63.3%）。两组妊娠率差异有统计学意义（P = 0.002）。ATT 可能会降低通过腹腔镜和/或宫腔镜检查诊断为 GTB 的患者的月经量和妊娠率。此外，ATT 并未改善慢性 GTB 患者的预后。
