Institute of Toxicology and Genetics, Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany.
Macromolecular Architectures, Institute for Chemical Technology and Polymer Chemistry, Karlsruhe Institute of Technology (KIT), Engesserstr. 18, 76128, Karlsruhe, Germany.
Macromol Rapid Commun. 2018 Jul;39(14):e1800231. doi: 10.1002/marc.201800231. Epub 2018 Jun 26.
A library of poly(methyl methacrylate)-block-polystyrene (PMMA-b-PS) block copolymers (BCPs) bearing small amounts (<10 mol%) of functional comonomer in either one or both blocks is investigated for their phase separation behavior in bulk and in thin films. Particularly, functionalities typically involved in modern postpolymerization modifications are considered, e.g., azide, pentafluorophenyl, furfuryl. Small-angle X-ray scattering and atomic force microscopy are employed to determine the characteristic dimensional features of lamellae-forming BCPs, which differ essentially in the functional groups. It is shown that the presence of the reactive moieties does not perturb the ability to phase separate in bulk, yet has an impact on the dimensions of the domains. Using a classic two-step procedure involving surface neutralization with a statistical PMMA-co-PS copolymer, it is observed that some functional copolymers are not able to form homogeneous thin films. Solvent stability and crosslinking ability of the films are then briefly assessed as a first step to establishing the functional films as nanoresolved molecular immobilization platform with feature sizes of 20 nm and below.
研究了一种含有少量(<10mol%)功能单体的聚甲基丙烯酸甲酯-聚苯乙烯(PMMA-b-PS)嵌段共聚物(BCP)库，以研究其在本体和薄膜中的相分离行为。特别是，考虑了通常涉及现代聚合后修饰的功能，例如叠氮化物、五氟苯基、糠基。小角 X 射线散射和原子力显微镜用于确定形成层状 BCP 的特征尺寸，这些 BCP 在功能基团上有本质区别。结果表明，反应性基团的存在不会干扰本体相分离的能力，但会影响畴的尺寸。使用经典的两步法，先用统计 PMMA-co-PS 共聚物进行表面中和，发现一些功能共聚物不能形成均匀的薄膜。然后简要评估了薄膜的溶剂稳定性和交联能力，作为将功能薄膜作为具有 20nm 及以下特征尺寸的纳米分辨分子固定化平台的第一步。
