[D-丙氨酸（2）-亮氨酸（5）-精氨酸（6）-脑啡肽的抗应激作用机制]
[Mechanism of the antistressor effect of D-Ala(2)-Leu(5)-Arg(6)-enkephalin].
作者信息
Lishmanov Iu B, Maslov L N, Titov M I
出版信息
Biull Eksp Biol Med. 1985 Sep;100(9):268-70.
PMID:2994775
Abstract
It has been shown that the stable analog of leu-enkephalin diminishes to a great extent the stress-induced changes in the blood content of ACTH, cortisol, hypophyseal-thyroid hormones, the CAMP level in the adrenal and thymic tissues of white rats. It is assumed that this circumstance may interfere with depletion of the adrenal cortex and suppression of the lymphoid-macrophagal system.
摘要
已经表明，亮氨酸脑啡肽的稳定类似物在很大程度上减少了应激引起的促肾上腺皮质激素、皮质醇、垂体-甲状腺激素血液含量的变化，以及大白鼠肾上腺和胸腺组织中环磷酸腺苷水平的变化。据推测，这种情况可能会干扰肾上腺皮质的耗竭和淋巴-巨噬细胞系统的抑制。
Zotero 插件